DCGI approves “2-deoxy-D-glucose (2-DG)” – an anti-COVID drug developed by DRDO

Contents

• 1
• 2 What is the News?
• 3 About 2-deoxy-D-glucose (2-DG):
• 4 Significance of this drug:

What is the News?

Defence Research and Development Organization(DRDO) has developed an anti-COVID drug named 2-deoxy-D-glucose(2-DG). Recently, the Drugs Controller General of India(DCGI) has approved this drug for emergency use.

About 2-deoxy-D-glucose (2-DG):

• 2-deoxy-D-glucose (2-DG) is an anti-Covid oral drug. It has been developed by the Institute of Nuclear Medicine and Allied Sciences (INMAS), a lab of DRDO in collaboration with Dr Reddy’s Laboratories(DRL).

How does a 2-DG drug work?

• The 2-DG comes in powder form in the sachet. One has to take it orally by dissolving the powder in water.
• The drug accumulates in the virus-infected cells. It, thereby, prevents virus growth by stopping viral synthesis and energy production.
• The selective accumulation of the drug in virally infected cells makes this drug unique.

Significance of this drug:

• The drug helps in the faster recovery of hospitalised patients. Further, it also reduces supplemental oxygen dependence.
• A higher proportion of patients treated with 2-DG also showed RT-PCR negative conversion in Covid-19 patients.

Source: Indian Express

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