Q. Which one of the following statements is correct regarding the Next Generation Sequencing (NGS)?
Red Book
Red Book

[A] It allows the simultaneous sequencing of millions of DNA fragments, providing high-throughput and rapid sequencing capabilities.

[B] It can only sequence a single DNA molecule at a time, making it a slow and labour-intensive process.

[C] It requires significantly more input DNA compared to traditional Sanger sequencing, limiting its use in clinical applications.

[D] It produces results with lower accuracy and longer turnaround times compared to older sequencing methods.

Answer: A
Notes:

Explanation – NGS is designed to sequence millions of DNA fragments simultaneously, which allows for rapid data generation and analysis. This high-throughput capability is a significant advantage over traditional sequencing methods. It is a revolutionary technology in the field of genomics that allows for the rapid and simultaneous sequencing of millions of DNA or RNA fragments.  

Source: The Hindu 

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