With reference to Controlled Human Infection Studies (CHIs) consider the following statements:1.CHIs involve deliberately infecting unhealthy individuals with various pathogens to study their effects and prevent the diseases further.2.CHIS have made important contributions to the treatment and prevention of many infectious diseases of global health importance.3.CHIS model can help provide unique insights into disease pathogenesis and can accelerate the development of novel medical interventions.Which of the statements given above are correct?

Q. With reference to Controlled Human Infection Studies (CHIs) consider the following statements:
1.CHIs involve deliberately infecting unhealthy individuals with various pathogens to study their effects and prevent the diseases further.
2.CHIS have made important contributions to the treatment and prevention of many infectious diseases of global health importance..
3.CHIS model can help provide unique insights into disease pathogenesis and can accelerate the development of novel medical interventions.
Which of the statements given above are correct?

[A] 1 and 2 only

[B] 2 and 3 only

[C] 1 and 3 only

[D] 1, 2 and 3

Answer: B

Notes:

Explanation –

Statement 1 is incorrect. In CHIS, healthy volunteers are intentionally exposed to pathogens in a controlled environment in order to promote understanding of the pathogenesis, transmission, prevention and treatment of infectious diseases in humans.

Statements 2 and 3 are correct. CHIS have a long history and have made important contributions to the treatment and prevention of many infectious diseases of global health importance. CHIS model can help provide unique insights into disease pathogenesis and can accelerate the development of novel medical interventions.

Source: ForumIAS

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