{"id":139267,"date":"2021-10-05T16:51:51","date_gmt":"2021-10-05T11:21:51","guid":{"rendered":"https:\/\/blog.forumias.com\/?p=139267"},"modified":"2021-10-05T16:56:28","modified_gmt":"2021-10-05T11:26:28","slug":"explained-nobel-prize-in-medicine-2021","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/explained-nobel-prize-in-medicine-2021\/","title":{"rendered":"Explained: Nobel Prize in Medicine 2021"},"content":{"rendered":"\n<p><b><span data-contrast=\"auto\">Context:<\/span><\/b><span data-contrast=\"auto\"> Two scientists David Julius and Ardem Patapoutian won the Nobel Prize in medicine 2021 on Monday for their discoveries into how the human body perceives temperature and touch. <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<h5><b><span data-contrast=\"auto\">About the discovery\u00a0<\/span><\/b><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/h5>\n<p><span data-contrast=\"auto\">Nobel prize in the medicine has been awarded for the\u00a0<\/span><b><span data-contrast=\"auto\">discoveries of<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><b><span data-contrast=\"auto\">receptors<\/span><\/b><span data-contrast=\"auto\">\u00a0for temperature and touch.\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Artificial sensors like thermometer are very common temperature sensors that can perceive changes in temperature. Similarly, in the human body, there are sensors to sense. However, only very specific proteins molecules relay these signals to the nervous system. These sensors were not identified yet.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Now scientists have discovered the molecular sensors in the human body that are sensitive to heat, and to mechanical pressure, and make us \u201cfeel\u201d hot or cold, or the touch of a sharp object on our skin.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<h5><b><span data-contrast=\"auto\">Mechanism of receptors <\/span><\/b><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/h5>\n<p><span data-contrast=\"auto\">Artificial detectors like a <strong>smoke detector<\/strong> send an alarm when it senses smoke beyond a certain threshold.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Similarly, when something hot or cold touches a body, <strong>heat receptors<\/strong> open up a passage for specific chemicals, like calcium ions, through the membrane of nerve cells. The <strong>chemical inside the cell<\/strong> causes a small change in electrical voltage, which is picked up by the nervous system. It enables the brain to perceive high temperatures.\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">These detectors can also <strong>detect temperature or pressure changes<\/strong> inside the body. For example, when our urinary bladder is full, the pressure in the bladder increases. This <strong>change in pressure<\/strong> is sensed by the <strong>pressure receptors<\/strong> and relayed to the nervous system which creates this urge to relieve oneself.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-139268 size-large\" src=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2021\/10\/press-medicine2021-figure2.jpg?resize=750%2C371&#038;ssl=1\" alt=\"\" width=\"750\" height=\"371\" srcset=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2021\/10\/press-medicine2021-figure2.jpg?resize=1024%2C506&amp;ssl=1 1024w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2021\/10\/press-medicine2021-figure2.jpg?resize=300%2C148&amp;ssl=1 300w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2021\/10\/press-medicine2021-figure2.jpg?resize=768%2C380&amp;ssl=1 768w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2021\/10\/press-medicine2021-figure2.jpg?resize=1536%2C759&amp;ssl=1 1536w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2021\/10\/press-medicine2021-figure2.jpg?resize=2048%2C1013&amp;ssl=1 2048w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2021\/10\/press-medicine2021-figure2.jpg?resize=1568%2C775&amp;ssl=1 1568w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2021\/10\/press-medicine2021-figure2.jpg?w=2250&amp;ssl=1 2250w\" sizes=\"auto, (max-width: 750px) 100vw, 750px\" \/><\/p>\n<h5><b><span data-contrast=\"auto\">Significance\u00a0of discovery<\/span><\/b><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/h5>\n<p><span data-contrast=\"auto\">Discoveries opened up \u201can entire field of\u00a0<\/span><b><span data-contrast=\"auto\">pharmacology<\/span><\/b><span data-contrast=\"auto\">\u201d.\u00a0The identification of these receptors opens up the\u00a0<\/span><b><span data-contrast=\"auto\">possibility of regulating their functionin<\/span><\/b><span data-contrast=\"auto\">g. Researchers are already working to develop drugs to\u00a0<\/span><b><span data-contrast=\"auto\">target the receptors<\/span><\/b><span data-contrast=\"auto\">\u00a0they identified.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">For example, there are receptors that make us feel pain,\u00a0if these receptors can be suppressed or made less effective, the person would feel less pain.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p>Read &#8211; <a href=\"https:\/\/forumias.com\/blog\/what-is-nobel-prize\/\">About Nobel Prizes\u00a0<\/a><\/p>\n<p><span data-contrast=\"auto\"><strong>Source<\/strong>: This post is based on the article\u00a0<strong>\u201cNobel Prize in Medicine 2021<\/strong><\/span><b><span data-contrast=\"auto\">\u201d<\/span><\/b><span data-contrast=\"auto\"> published in epaper.livemint.com<\/span><span data-contrast=\"auto\"> &amp; indianexpress on <\/span><b><span data-contrast=\"auto\">5th Oct 2021.<\/span><\/b><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Context: Two scientists David Julius and Ardem Patapoutian won the Nobel Prize in medicine 2021 on Monday for their discoveries into how the human body perceives temperature and touch. \u00a0 About the discovery\u00a0\u00a0 Nobel prize in the medicine has been awarded for the\u00a0discoveries of\u00a0receptors\u00a0for temperature and touch.\u00a0\u00a0 Artificial sensors like thermometer are very common temperature&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/explained-nobel-prize-in-medicine-2021\/\">Continue reading <span class=\"screen-reader-text\">Explained: Nobel Prize in Medicine 2021<\/span><\/a><\/p>\n","protected":false},"author":10308,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,9],"tags":[],"class_list":["post-139267","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-public","entry"],"jetpack_featured_media_url":"","views":{"total":0,"cached_at":"","cached_date":1700487376},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/139267","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10308"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=139267"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/139267\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=139267"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=139267"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=139267"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}