{"id":157656,"date":"2021-12-31T19:36:11","date_gmt":"2021-12-31T14:06:11","guid":{"rendered":"https:\/\/blog.forumias.com\/?p=157656"},"modified":"2021-12-31T19:36:11","modified_gmt":"2021-12-31T14:06:11","slug":"explained-two-new-vaccines-an-oral-pill-against-covid-19-and-how-they-work","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/explained-two-new-vaccines-an-oral-pill-against-covid-19-and-how-they-work\/","title":{"rendered":"Explained: Two new vaccines, an oral pill against Covid-19, and how they work"},"content":{"rendered":"

<\/b><\/p>\n


\nWhat is the news?<\/b><\/p>\n

India has approved two more Covid-19 vaccines, Corbevax and Covovax under emergency use authorization.It has also approved an antiviral drug, Molnupiravir to fight against COVID-19.<\/span><\/p>\n

Must Read: <\/b>What is Molnupiravir, the Covid-19 pill approved by India?<\/b><\/a><\/b><\/p>\n

What is Covovax Vaccine?<\/b><\/h5>\n

Covavax is manufactured by Serum Institute of India(SII) and has been developed by US-based Novavax.<\/span><\/p>\n

How does it work? <\/b>It is<\/span> a protein subunit vaccine that uses Recombinant Nanoparticle Technology (RNT).In this, harmless copies of the spike protein are grown in insect cells; the protein is then extracted and assembled into virus-like nanoparticles.<\/span><\/p>\n

Novavax has also used an immune-boosting compound (adjuvant).The same technology is used in HPV and the Hepatitis B vaccine.<\/span><\/p>\n

Efficacy: <\/b>Based on phase trials, it has an efficacy of 96.4% against the original virus strain, 86.3% against Alpha and 89.7% efficacy overall.<\/span><\/p>\n\n\n\n
Must Read:<\/b> DGCI approved Corbevax Vaccine<\/span><\/b><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
What is Protein Sub-unit Vaccine and what are its drawbacks?<\/b><\/h5>\n

Protein subunit vaccines are made by isolating a piece of the actual virus<\/strong>. As fragments are used, there is no danger that these will multiply within the body. These pieces are expected to trigger an immune response that will hopefully prevent future infection.\u00a0<\/span><\/p>\n

A downside to subunits is that because they contain only a part of the virus<\/strong>, they may miss certain characteristic signatures of the virus and the immune system may fail to recognise them. This problem is overcome by using adjuvant or booster shots.<\/strong>\u00a0<\/span><\/p>\n

Another weakness is that these vaccines don\u2019t infect the cells<\/strong> (like inactivated DNA or mRNA vaccines)<\/em> and therefore doesn\u2019t elicit the long-lasting immunity conferred by cells (or the T-cell response)<\/em>.<\/span><\/p>\n

Source:<\/b>This post is based on the article <\/span>\u2018Explained: Two new vaccines, an oral pill against Covid-19, and how they work\u2019 <\/b>published in Indian Express <\/b>on 31st<\/sup> Dec 2021.<\/b><\/p>\n","protected":false},"excerpt":{"rendered":"

What is the news? India has approved two more Covid-19 vaccines, Corbevax and Covovax under emergency use authorization.It has also approved an antiviral drug, Molnupiravir to fight against COVID-19. Must Read: What is Molnupiravir, the Covid-19 pill approved by India? What is Covovax Vaccine? Covavax is manufactured by Serum Institute of India(SII) and has been… Continue reading Explained: Two new vaccines, an oral pill against Covid-19, and how they work<\/span><\/a><\/p>\n","protected":false},"author":10317,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,9],"tags":[10500],"class_list":["post-157656","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-public","tag-indian-express","entry"],"jetpack_featured_media_url":"","views":{"total":0,"cached_at":"","cached_date":1704920212},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/157656","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10317"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=157656"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/157656\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=157656"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=157656"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=157656"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}