{"id":198333,"date":"2022-08-02T19:34:36","date_gmt":"2022-08-02T14:04:36","guid":{"rendered":"https:\/\/blog.forumias.com\/?p=198333"},"modified":"2022-08-02T19:34:36","modified_gmt":"2022-08-02T14:04:36","slug":"explained-alphafold-a-tour-de-force-in-science","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/explained-alphafold-a-tour-de-force-in-science\/","title":{"rendered":"Explained| AlphaFold: A tour de force in science"},"content":{"rendered":"\n

Source: <\/b>The post is based on the article <\/span>\u201cExplained| AlphaFold: A tour de force in science<\/b>\u201d <\/b>published in <\/span>The Hindu <\/b>on 2nd August 2022.<\/b><\/p>\n

What is the News?<\/b><\/h5>\n

DeepMind, a company based in London and owned by Google announced that it had predicted the three-dimensional structures of more than 200 million proteins using AlphaFold.<\/span><\/p>\n

What is AlphaFold?<\/b><\/h5>\n

AlphaFold is an AI-based protein structure prediction tool. It is based on a computer system called <\/span>deep neural network.\u00a0<\/span><\/a><\/p>\n

How does AlphaFold work?<\/b><\/h5>\n

It uses processes based on \u201ctraining, learning, retraining and relearning\u201d. <\/span>By using this method, AlphaFold has now predicted the structures of the entire 214 million unique protein sequences deposited in the Universal Protein Resource(UniProt) database.<\/span><\/p>\n

What are the implications of this development?<\/b><\/h5>\n

Proteins are the business ends of biology, meaning proteins carry out all the functions inside a living cell. Therefore, knowing protein structure and function is essential to understanding human diseases.\u00a0<\/span><\/p>\n

Scientists predict protein structures using x-ray crystallography, nuclear magnetic resonance spectroscopy, or cryogenic electron microscopy.\u00a0<\/span><\/p>\n

These techniques are not just time-consuming, they often take years and are based mainly on trial-and-error methods.<\/span><\/p>\n

Therefore, the development of AlphaFold changes all of that. It is a watershed movement in science and structural biology in particular.<\/span><\/p>\n

Is AlphaFold the only tool for predicting protein structures?<\/b><\/h5>\n

AlphaFold is neither flawless nor the only AI-based protein structure prediction tool.<\/span><\/p>\n

RoseTTaFold, developed at the University of Washington in Seattle, U.S., is another tool. Although less accurate than AlphaFold, it can predict the structure of protein complexes.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Source: The post is based on the article \u201cExplained| AlphaFold: A tour de force in science\u201d published in The Hindu on 2nd August 2022. What is the News? DeepMind, a company based in London and owned by Google announced that it had predicted the three-dimensional structures of more than 200 million proteins using AlphaFold. What… Continue reading Explained| AlphaFold: A tour de force in science<\/span><\/a><\/p>\n","protected":false},"author":10317,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738,9],"tags":[10498],"class_list":["post-198333","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","category-public","tag-the-hindu","entry"],"jetpack_featured_media_url":"","views":{"total":0,"cached_at":"","cached_date":1704955223},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/198333","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10317"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=198333"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/198333\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=198333"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=198333"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=198333"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}