{"id":203193,"date":"2022-09-02T19:23:25","date_gmt":"2022-09-02T13:53:25","guid":{"rendered":"https:\/\/blog.forumias.com\/?p=203193"},"modified":"2022-09-02T19:23:25","modified_gmt":"2022-09-02T13:53:25","slug":"hydration-of-proteins-could-act-as-a-potential-marker-for-an-early-detection-of-neuro-degenerative-diseases","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/hydration-of-proteins-could-act-as-a-potential-marker-for-an-early-detection-of-neuro-degenerative-diseases\/","title":{"rendered":"Hydration of proteins could act as a potential marker for an early detection of neuro-degenerative diseases"},"content":{"rendered":"\n<p><b>Source: <\/b><span style=\"font-weight: 400;\">The post is based on the article <\/span><b>\u201c<\/b><b>Hydration of proteins could act as a potential marker for an early detection of neuro-degenerative diseases<\/b><b>\u201d <\/b><span style=\"font-weight: 400;\">published in <\/span><b>PIB <\/b>on<b> 1st\u00a0 September 2022.<\/b><\/p>\n<h5><b>What is the News?<\/b><\/h5>\n<p><span style=\"font-weight: 400;\">A study has found that hydration dynamics of proteins play a pivotal role in the aggregation of several proteins which is a preliminary step toward various neurodegenerative diseases<\/span><\/p>\n<h5><b>What is Liquid-Liquid<\/b><b>\u00a0Phase Separation(LLPS)?<\/b><\/h5>\n<p><span style=\"font-weight: 400;\">Liquid-Liquid Phase Separation(LLPS) is<\/span><span style=\"font-weight: 400;\"> a self-aggregated system. It is an intermediate step during the formation of stable protein aggregates.\u00a0\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This process plays an important role in the formation of cells organelles like P bodies, nucleolus which are membrane-less compartments in the cytoplasm of cells<\/span><\/p>\n<p><b>LLPS and neurodegenerative diseases<\/b><span style=\"font-weight: 400;\">: Protein aggregation is the main hallmark of neurodegenerative diseases. Many proteins found in pathological inclusions are known to undergo liquid-liquid phase separation.<\/span><\/p>\n<h5><b>What is the study conducted by scientists?<\/b><\/h5>\n<p><span style=\"font-weight: 400;\">Scientists have explored how the hydration of proteins gets altered as LLPS sets in.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">They found that hydration dynamics of proteins play a pivotal role in the aggregation of several proteins which is a preliminary step toward various neurodegenerative diseases.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Thus, the aggregation process could be spotted early by detecting altering water network dynamics and modulated using inactive substances that serve as the vehicle or medium for a drug or other active substance.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source: The post is based on the article \u201cHydration of proteins could act as a potential marker for an early detection of neuro-degenerative diseases\u201d published in PIB on 1st\u00a0 September 2022. What is the News? A study has found that hydration dynamics of proteins play a pivotal role in the aggregation of several proteins which&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/hydration-of-proteins-could-act-as-a-potential-marker-for-an-early-detection-of-neuro-degenerative-diseases\/\">Continue reading <span class=\"screen-reader-text\">Hydration of proteins could act as a potential marker for an early detection of neuro-degenerative diseases<\/span><\/a><\/p>\n","protected":false},"author":10317,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738,9],"tags":[3590],"class_list":["post-203193","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","category-public","tag-pib","entry"],"jetpack_featured_media_url":"","views":{"total":0,"cached_at":"","cached_date":1704729148},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/203193","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10317"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=203193"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/203193\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=203193"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=203193"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=203193"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}