{"id":203754,"date":"2022-09-06T18:45:15","date_gmt":"2022-09-06T13:15:15","guid":{"rendered":"https:\/\/blog.forumias.com\/?p=203754"},"modified":"2022-09-06T18:45:15","modified_gmt":"2022-09-06T13:15:15","slug":"bpal-trial-confirms-a-new-therapy-regime-can-work-for-drug-resistant-tb","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/bpal-trial-confirms-a-new-therapy-regime-can-work-for-drug-resistant-tb\/","title":{"rendered":"BPaL: Trial confirms a new therapy regime can work for drug-resistant TB"},"content":{"rendered":"\n

Source: <\/b>The post is based on the article <\/span>\u201cTrial confirms a new therapy regime can work for drug-resistant TB\u201d <\/b>published in<\/span> Indian Express <\/b>on 2nd September 2022<\/b><\/p>\n

What is the News?<\/b><\/h5>\n

A short treatment regimen of six months called BPaL has shown favourable outcomes in <\/span>highly drug-resistant tuberculosis patients.<\/span><\/p>\n

What is BPaL?<\/b><\/h5>\n

Developed by<\/b>: TB Alliance, a not-for-profit organization\u00a0<\/span><\/p>\n

Purpose<\/b>: BPaL is a 6-month, all-oral, three-drug regimen that is used to treat people with highly drug-resistant forms of TB.\u00a0<\/span><\/p>\n

Composition<\/b>: BPaL is a combination of three newer antibiotics, namely bedaquiline, pretomanid and linezolid.\u00a0<\/span><\/p>\n

Note:<\/b> Drug-resistant TB develops when the long, complex, decades-old TB drug regimen is improperly administered or when people contract TB from others who have drug-resistant disease.<\/span><\/p>\n

What is the significance of BPaL?<\/b><\/h5>\n

Firstly, <\/b>BPaL will drastically cut short the treatment duration by half (and more) and reduce the amount of medication an MDR-TB patient must take during treatment. Hence, from a treatment duration of 18 to 24 months, the BPaL is likely to bring down treatment time to around six months.<\/span><\/p>\n

Secondly, <\/b>the older all-oral drug regimen included nearly 14 different anti-TB drugs for a patient to take every day. With BPaL, it is likely to take just three daily tablets. Hence, a shorter regimen which is all oral and requires lesser doses per day makes it easier for a patient to adhere to and complete treatment.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Source: The post is based on the article \u201cTrial confirms a new therapy regime can work for drug-resistant TB\u201d published in Indian Express on 2nd September 2022 What is the News? A short treatment regimen of six months called BPaL has shown favourable outcomes in highly drug-resistant tuberculosis patients. What is BPaL? Developed by: TB… Continue reading BPaL: Trial confirms a new therapy regime can work for drug-resistant TB<\/span><\/a><\/p>\n","protected":false},"author":10317,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738,9],"tags":[10500],"class_list":["post-203754","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","category-public","tag-indian-express","entry"],"jetpack_featured_media_url":"","views":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/203754","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10317"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=203754"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/203754\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=203754"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=203754"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=203754"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}