{"id":218357,"date":"2022-12-14T19:09:52","date_gmt":"2022-12-14T13:39:52","guid":{"rendered":"https:\/\/blog.forumias.com\/?p=218357"},"modified":"2022-12-14T19:09:52","modified_gmt":"2022-12-14T13:39:52","slug":"what-is-base-editing-the-groundbreaking-tech-that-cleared-a-teenagers-cancer","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/what-is-base-editing-the-groundbreaking-tech-that-cleared-a-teenagers-cancer\/","title":{"rendered":"What is base editing, the groundbreaking tech that cleared a teenager\u2019s cancer?"},"content":{"rendered":"\n

Source: <\/b>The post is based on the article<\/span> \u201cWhat is base editing, the groundbreaking tech that cleared a teenager\u2019s cancer?\u201d <\/b>published in<\/span> Indian Express <\/b>on 14th December 2022<\/b><\/p>\n

What is the News?<\/b><\/h5>\n

In the UK, a teenage girl’s <\/span>incurable blood cancer has been cleared from her body through the first use of a revolutionary type of method called Base Editing.<\/span><\/p>\n

About the T-cell acute lymphoblastic leukaemia(T-ALL)<\/b><\/h5>\n

The girl was diagnosed with a kind of blood cancer known as T-cell acute lymphoblastic leukaemia(T-ALL).\u00a0<\/span><\/p>\n

T-ALL affects the stem cells in the bone marrow that produce a particular kind of white blood cells (WBC) called T lymphocytes (T cells). These cells provide a person immunity by killing cells carrying infections, activating other immune cells, and regulating the immune response.<\/span><\/p>\n

Note:<\/b> While found in both children and adults, T-ALL\u2019s incidence decreases with age.<\/span><\/p>\n

How is T-ALL typically treated?<\/b><\/h5>\n

Typical treatment for T-ALL is similar to that of any leukaemia\u2013 chemotherapy and stem cell\/bone marrow transplant.\u00a0<\/span><\/p>\n

Doctors will first administer multiple rounds of chemotherapy. This either kills the cancerous cells or stops them from further dividing. The exact schedule is guided by an individual\u2019s age and general health. If this fails, and the individual is suitable, doctors will conduct a bone marrow transplant.\u00a0<\/span><\/p>\n

Overall treatment for T-ALL is pretty effective\u2013 children have a survival rate of over 85% after five years of receiving this treatment. Unfortunately, the teenage girl lay in the unlucky 15% of children where the treatment just did not work.<\/span><\/p>\n

The doctors then <\/span>used a technology called <\/span>base editing<\/b>, which was <\/span>invented only six years ago<\/span>.<\/span><\/p>\n

What is Base Editing Technique?<\/b><\/h5>\n
\"Base
Source: BBC<\/figcaption><\/figure>\n

Bases are the language of life. The four types of base – adenine (A), cytosine (C), guanine (G) and thymine (T) – are the building blocks of the human genetic code. Just as letters in the alphabet spell out <\/span>words that carry meaning, the billions of bases in human DNA spell out the instruction manual for every human body.\u00a0<\/span><\/p>\n

Base editing allows scientists to zoom into a precise part of the genetic code and then alter the molecular structure of just one base, converting it into another and changing the genetic instructions.\u00a0<\/span><\/p>\n

The doctors in the UK used this tool to engineer a new type of T-cell that was capable of hunting down and killing teenage girl’s cancerous T-cells.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Source: The post is based on the article \u201cWhat is base editing, the groundbreaking tech that cleared a teenager\u2019s cancer?\u201d published in Indian Express on 14th December 2022 What is the News? In the UK, a teenage girl’s incurable blood cancer has been cleared from her body through the first use of a revolutionary type… Continue reading What is base editing, the groundbreaking tech that cleared a teenager\u2019s cancer?<\/span><\/a><\/p>\n","protected":false},"author":10317,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738,9],"tags":[10500],"class_list":["post-218357","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","category-public","tag-indian-express","entry"],"jetpack_featured_media_url":"","views":{"total":0,"cached_at":"","cached_date":1703900822},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/218357","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10317"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=218357"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/218357\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=218357"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=218357"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=218357"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}