{"id":218489,"date":"2022-12-15T20:05:08","date_gmt":"2022-12-15T14:35:08","guid":{"rendered":"https:\/\/blog.forumias.com\/?p=218489"},"modified":"2022-12-15T20:05:08","modified_gmt":"2022-12-15T14:35:08","slug":"how-gene-therapy-could-cure-cancer","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/how-gene-therapy-could-cure-cancer\/","title":{"rendered":"How gene therapy could cure cancer"},"content":{"rendered":"\n<p><b>Source: <\/b><span style=\"font-weight: 400;\">The post is based on the article<\/span><b> \u201cHow gene therapy could cure cancer<\/b><b>\u201d <\/b><span style=\"font-weight: 400;\">published in <\/span><b>The Hindu <\/b>on<b> 15th December 2022<\/b><\/p>\n<h5><b>What is the News?<\/b><\/h5>\n<p><span style=\"font-weight: 400;\">Scientists in the United Kingdom have tested a new form of experimental gene therapy technique called <\/span><b>Base Editing <\/b><span style=\"font-weight: 400;\">to create cancer in a teenage girl.<\/span><\/p>\n<h5><b>About T-cell acute lymphoblastic leukaemia (T-ALL)<\/b><\/h5>\n<p><span style=\"font-weight: 400;\">The was suffering from a blood cancer known as <\/span><b>T-cell acute lymphoblastic leukaemia (T-ALL).\u00a0<\/b><\/p>\n<p><span style=\"font-weight: 400;\">In this form of blood cancer, the T-cells, which are a class of white blood cells, equipped to hunt and neutralize threats to the body, turn against the body and end up destroying healthy cells that normally help with immunity.\u00a0<\/span><\/p>\n<h5><b>What is \u2018base editing?\u2019<\/b><\/h5>\n<p><span style=\"font-weight: 400;\">A person\u2019s genetic code is several permutations of four bases: Adenine (A), Guanin (G), cytosine (C) and thymine (T).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Sequences of these bases, akin to letters in the alphabet, spell out genes that are instructions to produce the wide array of proteins necessary for the body\u2019s functions.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In the girl\u2019s case, her T-cells \u2014 perhaps because of a mis-arrangement in the sequence of bases \u2014 had become cancerous. A way to correct this mis-arrangement could mean a healthier immune system.\u00a0<\/span><\/p>\n<h5><b>How did base-editing work?<\/b><\/h5>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 100%;\"><strong>Read here: <a title=\"What is base editing, the groundbreaking tech that cleared a teenager\u2019s cancer?\" href=\"https:\/\/forumias.com\/blog\/what-is-base-editing-the-groundbreaking-tech-that-cleared-a-teenagers-cancer\/\">What is base editing, the groundbreaking tech that cleared a teenager\u2019s cancer?<\/a><\/strong><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"font-weight: 400;\">After spending a month in remission, she was given a second donor transplant to regrow her immune system which would contain healthy T-cells.<\/span><\/p>\n<p><b>How effective was the treatment?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">It has been 1.5 years since she was first diagnosed with the disease and whether the treatment has reliably and entirely fixed her immune system, remains to be established.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source: The post is based on the article \u201cHow gene therapy could cure cancer\u201d published in The Hindu on 15th December 2022 What is the News? Scientists in the United Kingdom have tested a new form of experimental gene therapy technique called Base Editing to create cancer in a teenage girl. About T-cell acute lymphoblastic&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/how-gene-therapy-could-cure-cancer\/\">Continue reading <span class=\"screen-reader-text\">How gene therapy could cure cancer<\/span><\/a><\/p>\n","protected":false},"author":10317,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738,9],"tags":[10498],"class_list":["post-218489","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","category-public","tag-the-hindu","entry"],"jetpack_featured_media_url":"","views":{"total":0,"cached_at":"","cached_date":1704785230},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/218489","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10317"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=218489"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/218489\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=218489"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=218489"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=218489"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}