{"id":219316,"date":"2022-12-21T19:25:25","date_gmt":"2022-12-21T13:55:25","guid":{"rendered":"https:\/\/blog.forumias.com\/?p=219316"},"modified":"2022-12-21T19:25:25","modified_gmt":"2022-12-21T13:55:25","slug":"explained-how-can-mrna-vaccines-help-fight-cancer","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/explained-how-can-mrna-vaccines-help-fight-cancer\/","title":{"rendered":"Explained | How can mRNA vaccines help fight cancer?"},"content":{"rendered":"\n<p><b>Source: <\/b><span style=\"font-weight: 400;\">The post is based on the article <\/span><b>\u201cExplained | How can mRNA vaccines help fight cancer?\u201d<\/b><span style=\"font-weight: 400;\"> published in <\/span><b>The Hindu <\/b>on<b> 20th December 2022<\/b><\/p>\n<h5><b>What is the News?<\/b><\/h5>\n<p><span style=\"font-weight: 400;\">The results of a trial of an experimental <\/span><a href=\"https:\/\/forumias.com\/blog\/gennovas-mrna-vaccine-gets-clearance-for-phase-2-3-clinical-trials\/\"><span style=\"font-weight: 400;\">mRNA (messenger ribonucleic acid) <\/span><\/a><span style=\"font-weight: 400;\">cancer vaccine made by Moderna and MSD (Merck &amp; Co.) taken along with <\/span><span style=\"font-weight: 400;\">immunotherapy drug Keytruda has shown promising results against advanced melanoma, a kind of skin cancer.<\/span><\/p>\n<h5><b>What is <\/b><b>mRNA (messenger ribonucleic acid) cancer vaccine?<\/b><\/h5>\n<p><span style=\"font-weight: 400;\">It is a personalised cancer vaccine which means it is tailor-made for every patient.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">To build the vaccine, researchers took samples of patients&#8217; tumours and healthy tissue.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">After analyzing the samples to decode their genetic sequence and isolate mutant proteins associated only with cancer, that information was used to design a tailor-made cancer vaccine.<\/span><\/p>\n<p><b>Note:<\/b><span style=\"font-weight: 400;\"> This vaccine uses the same messenger-RNA technology that was used to produce the COVID vaccine.\u00a0<\/span><\/p>\n<h5><b>How does the vaccine work?<\/b><\/h5>\n<p><span style=\"font-weight: 400;\">The personalised cancer vaccine works in concert with Keytruda, to disable a protein called Programmed Death 1 (PD-1), which helps tumours to evade the immune system.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When injected into a patient, the patient\u2019s cells act as a manufacturing plant, producing perfect copies of the mutations for the immune system to recognise and destroy the cancer cells.<\/span><\/p>\n<h5><b>What is the significance of this vaccine?<\/b><\/h5>\n<p><span style=\"font-weight: 400;\">The vaccine has shown a 44% reduction in the risk of dying of cancer or having cancer progress. <\/span><span style=\"font-weight: 400;\">Hence, this could lead to new ways to fight other types of cancers too.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source: The post is based on the article \u201cExplained | How can mRNA vaccines help fight cancer?\u201d published in The Hindu on 20th December 2022 What is the News? The results of a trial of an experimental mRNA (messenger ribonucleic acid) cancer vaccine made by Moderna and MSD (Merck &amp; Co.) taken along with immunotherapy&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/explained-how-can-mrna-vaccines-help-fight-cancer\/\">Continue reading <span class=\"screen-reader-text\">Explained | How can mRNA vaccines help fight cancer?<\/span><\/a><\/p>\n","protected":false},"author":10317,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738,9],"tags":[10498],"class_list":["post-219316","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","category-public","tag-the-hindu","entry"],"jetpack_featured_media_url":"","views":{"total":0,"cached_at":"","cached_date":1702372211},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/219316","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10317"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=219316"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/219316\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=219316"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=219316"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=219316"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}