{"id":242389,"date":"2023-05-15T19:21:05","date_gmt":"2023-05-15T13:51:05","guid":{"rendered":"https:\/\/blog.forumias.com\/?p=242389"},"modified":"2023-05-15T19:21:05","modified_gmt":"2023-05-15T13:51:05","slug":"explaining-mitochondrial-donation-treatment-how-a-baby-has-three-parents","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/explaining-mitochondrial-donation-treatment-how-a-baby-has-three-parents\/","title":{"rendered":"Explaining mitochondrial donation treatment: how a baby has three parents"},"content":{"rendered":"\n<p><b>Source: <\/b>T<span style=\"font-weight: 400;\">he post is based on the article <\/span><b>\u201cExplaining mitochondrial donation treatment: how a baby has three parents\u201d <\/b><span style=\"font-weight: 400;\">published in <\/span><b>The Hindu <\/b>on <b>15th May 2023<\/b><\/p>\n<h2><b>What is the News?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">A baby has been born in the UK using a technique called Mitochondrial Donation Treatment (MDT) (popularly called \u2018Three Parents Baby\u2019).<\/span><\/p>\n<h2><b>Why do parents go for Mitochondrial Donation Treatment (MDT)?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Mitochondria are basically the powerhouses of the cells. They generate energy and thus are also responsible for cell function in the human body.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Certain defects might occur impacting the way the mitochondria produce energy for the cells (especially in the \u2018energy-hungry\u2019 tissues of the brain, nerves, muscles, kidneys, heart, liver), and thereby impacting cell function. The diseases that arise out of such mitochondrial mutations are called mitochondrial diseases.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some estimates put the incidence of mitochondrial diseases as one in 5,000 people.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Mitochondrial diseases are only <\/span><b>passed on by the mother to their children.<\/b><\/p>\n<p><span style=\"font-weight: 400;\">In this case, the mother had mitochondrial disease, and she was intent on not passing it on to her baby. She also did not want to have a donor egg, for the baby would carry the genetic material of the donor.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">So, they went for <\/span><span style=\"font-weight: 400;\">Mitochondrial Donation Treatment (MDT).<\/span><\/p>\n<h2><b>How does Mitochondrial Donation Treatment (MDT) work?<\/b><\/h2>\n<figure id=\"attachment_242397\" aria-describedby=\"caption-attachment-242397\" style=\"width: 640px\" class=\"wp-caption alignleft\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"wp-image-242397 size-full\" src=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2023\/05\/image-253.jpg?resize=640%2C591&#038;ssl=1\" alt=\"Mitochondrial Donation Treatment (MDT)\" width=\"640\" height=\"591\" srcset=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2023\/05\/image-253.jpg?w=640&amp;ssl=1 640w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2023\/05\/image-253.jpg?resize=300%2C277&amp;ssl=1 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><figcaption id=\"caption-attachment-242397\" class=\"wp-caption-text\">Source: Reuters<\/figcaption><\/figure>\n<p><span style=\"font-weight: 400;\">Firstly,<\/span><span style=\"font-weight: 400;\"> through an advanced in vitro fertilisation technique, the baby\u2019s biological father\u2019s sperm was used to fertilize the eggs from the biological mother, who has mitochondrial disease and a third, female donor with clear mitochondria, separately.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Then, the nuclear genetic material from the donor\u2019s egg is removed and replaced with the genetic material from the biological parents.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The final product \u2014 the egg \u2014 which has the genetic material (DNA) from the parents and the mitochondria from the female donor, is implanted in the uterus and carried to full term to yield a <\/span><span style=\"font-weight: 400;\">baby who will be free from the mother\u2019s mitochondrial disease. This process is termed Mitochondrial Donation Treatment (MDT).<\/span><\/p>\n<p><b>Are there any side effects to the MDT procedure?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">S<\/span><span style=\"font-weight: 400;\">ometimes it is possible that a small amount of the maternal mitochondria with errors may get passed on during the procedure. However, more data <\/span><span style=\"font-weight: 400;\">is needed to establish consensus on this.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source: The post is based on the article \u201cExplaining mitochondrial donation treatment: how a baby has three parents\u201d published in The Hindu on 15th May 2023 What is the News? A baby has been born in the UK using a technique called Mitochondrial Donation Treatment (MDT) (popularly called \u2018Three Parents Baby\u2019). Why do parents go&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/explaining-mitochondrial-donation-treatment-how-a-baby-has-three-parents\/\">Continue reading <span class=\"screen-reader-text\">Explaining mitochondrial donation treatment: how a baby has three parents<\/span><\/a><\/p>\n","protected":false},"author":10317,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738,9],"tags":[10498],"class_list":["post-242389","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","category-public","tag-the-hindu","entry"],"jetpack_featured_media_url":"","views":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/242389","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10317"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=242389"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/242389\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=242389"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=242389"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=242389"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}