{"id":242570,"date":"2023-05-16T21:13:05","date_gmt":"2023-05-16T15:43:05","guid":{"rendered":"https:\/\/blog.forumias.com\/?p=242570"},"modified":"2023-05-16T21:13:05","modified_gmt":"2023-05-16T15:43:05","slug":"donanemab-the-new-alzheimers-drug","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/donanemab-the-new-alzheimers-drug\/","title":{"rendered":"Donanemab: The New Alzheimer&#8217;s Drug"},"content":{"rendered":"\n<p><b>Source: <\/b><span style=\"font-weight: 400;\">The post is based on the article <\/span><b>\u201cThe New Alzheimer&#8217;s Drug\u201d <\/b><span style=\"font-weight: 400;\">published in<\/span><b> The Hindu <\/b>on <b>16th May 2023<\/b><\/p>\n<h2><b>What is the News?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">A second drug named \u201c<\/span><b>Donanemab<\/b><span style=\"font-weight: 400;\">\u201d has been found effective in checking cognitive decline in people with early Alzheimer\u2019s disease.<\/span><\/p>\n<h2><b>What is Alzheimer Disease?<\/b><\/h2>\n<p><a href=\"https:\/\/forumias.com\/blog\/aducanumab-approved-by-usfda-for-alzheimers-disease\/\"><b>Click Here to read<\/b><\/a><\/p>\n<p><span style=\"font-weight: 400;\">An estimate suggests that India\u2019s burden of dementia, of which Alzheimer\u2019s is a part, will increase to 14 million by 2050.<\/span><\/p>\n<h2><b>What is Donanemab?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Donanemab is a drug being developed to treat people with early Alzheimer\u2019s disease.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The drug is being developed by the U.S.-based pharmaceutical giant Eli Lill.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The drug works by targeting a common hallmark of Alzheimer\u2019s disease in the brain: amyloid plaques.<\/span><\/p>\n<p><em><b>Note: <\/b><span style=\"font-weight: 400;\">Beta-amyloid is a protein which plays an important role in brain function for everyone. But in patients with Alzheimer\u2019s disease, beta-amyloid turns toxic \u2013 clumping together and disrupting the connection between brain cells and their function. This leads to cognitive issues such as memory loss.<\/span><\/em><\/p>\n<p><b>Significance:<\/b><span style=\"font-weight: 400;\"> Donanemab has been found to slow down cognitive decline by 35% when compared with a placebo in a phase III trial.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u2013 This is the second drug, within a span of one year, that has been found to be effective in checking cognitive decline in people with Alzheimer\u2019s disease.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u2013 However, it is important to note that the two drugs don\u2019t stop or reverse Alzheimers.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source: The post is based on the article \u201cThe New Alzheimer&#8217;s Drug\u201d published in The Hindu on 16th May 2023 What is the News? A second drug named \u201cDonanemab\u201d has been found effective in checking cognitive decline in people with early Alzheimer\u2019s disease. What is Alzheimer Disease? Click Here to read An estimate suggests that&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/donanemab-the-new-alzheimers-drug\/\">Continue reading <span class=\"screen-reader-text\">Donanemab: The New Alzheimer&#8217;s Drug<\/span><\/a><\/p>\n","protected":false},"author":10317,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738,9],"tags":[10498],"class_list":["post-242570","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","category-public","tag-the-hindu","entry"],"jetpack_featured_media_url":"","views":{"total":0,"cached_at":"","cached_date":1700464584},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/242570","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10317"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=242570"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/242570\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=242570"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=242570"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=242570"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}