{"id":270702,"date":"2023-11-23T20:27:18","date_gmt":"2023-11-23T14:57:18","guid":{"rendered":"https:\/\/forumias.com\/blog\/?p=270702"},"modified":"2023-11-23T20:27:18","modified_gmt":"2023-11-23T14:57:18","slug":"amyloidosis-scientists-fabricate-2d-protein-monolayer-that-can-help-to-study-diseases-like-amyloidosis","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/amyloidosis-scientists-fabricate-2d-protein-monolayer-that-can-help-to-study-diseases-like-amyloidosis\/","title":{"rendered":"Amyloidosis: Scientists fabricate 2D protein monolayer that can help to study diseases like Amyloidosis"},"content":{"rendered":"<p><b>Source: <\/b><span style=\"font-weight: 400;\">The post is based on the article <\/span><b>\u201c<\/b><b>Amyloidosis: Scientists fabricate 2D protein monolayer that can help to study diseases like Amyloidosis<\/b><b>\u201d <\/b><span style=\"font-weight: 400;\">published in <\/span><b>\u201cPIB\u201d on 22nd November 2023.<\/b><\/p>\n<h2><b>Why in the News?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Scientists have created a <strong>2D protein monolayer by assembling lysozyme molecules<\/strong>. This can help study diseases such as Amyloidosis.<\/span><\/p>\n<h2><b>What is Amyloidosis?<\/b><\/h2>\n<table>\n<tbody>\n<tr>\n<td><b>Specifications<\/b><\/td>\n<td><b>Details<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Definition<\/b><\/td>\n<td><span style=\"font-weight: 400;\">It is a<\/span><span style=\"font-weight: 400;\"><strong> rare disease<\/strong> that <strong>occurs when a protein called amyloid builds up in organs<\/strong>. This amyloid buildup can make the organs not work properly.<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Affected organs<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Organs that may be affected include the heart, kidneys, liver, spleen, nervous system and digestive tract.<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Causes<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Secondary to a different health condition or can develop as a primary condition. Sometimes it is due to a mutation in a gene.<\/span><\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\"><b>Types<\/b><\/td>\n<td><b>AL (primary) amyloidosis<\/b><span style=\"font-weight: 400;\">: People with conditions such as multiple myeloma or a bone marrow illness are more likely to have this.<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>AA (secondary) amyloidosis<\/b><span style=\"font-weight: 400;\">: It is caused by fragments of amyloid A protein and affects the kidneys in about 80 percent of cases.\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Transthyretin amyloidosis (ATTR)<\/b><span style=\"font-weight: 400;\">: It can be inherited from a family member. People of African descent may be more likely to carry the gene.<br \/>\n<\/span><span style=\"font-weight: 400;\"><strong>Note:<\/strong> Transthyretin is a protein that is also known as prealbumin. It is made in the liver.\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Treatment<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Chemotherapy, Bone Marrow Transplant and medications.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><b>What is <\/b><b>Lysozyme?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">1) Lysozyme is a <strong>protein present in mucosal secretions<\/strong>. It is <\/span><span style=\"font-weight: 400;\">found in various bodily fluids like tears, saliva, mucus and human milk.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">2) It plays a <strong>crucial role in the body&#8217;s defense system<\/strong> by breaking down bacterial cell walls and acting as an antimicrobial agent.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">3) Large amounts of lysozyme can be <strong>found in egg white<\/strong>.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">4) It can be regarded as a <strong>model protein in studying diseases like Amyloidosis<\/strong>.<\/span><\/p>\n<p><strong>UPSC Syllabus:<\/strong> Diseases in News<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source: The post is based on the article \u201cAmyloidosis: Scientists fabricate 2D protein monolayer that can help to study diseases like Amyloidosis\u201d published in \u201cPIB\u201d on 22nd November 2023. Why in the News? Scientists have created a 2D protein monolayer by assembling lysozyme molecules. This can help study diseases such as Amyloidosis. What is Amyloidosis?&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/amyloidosis-scientists-fabricate-2d-protein-monolayer-that-can-help-to-study-diseases-like-amyloidosis\/\">Continue reading <span class=\"screen-reader-text\">Amyloidosis: Scientists fabricate 2D protein monolayer that can help to study diseases like Amyloidosis<\/span><\/a><\/p>\n","protected":false},"author":10317,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,9],"tags":[11872],"class_list":["post-270702","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-public","tag-9pm-daily-factly","entry"],"jetpack_featured_media_url":"","views":{"total":3,"cached_at":"","cached_date":1700768259},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/270702","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10317"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=270702"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/270702\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=270702"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=270702"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=270702"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}