{"id":273689,"date":"2023-12-13T18:16:37","date_gmt":"2023-12-13T12:46:37","guid":{"rendered":"https:\/\/forumias.com\/blog\/?p=273689"},"modified":"2023-12-13T18:16:37","modified_gmt":"2023-12-13T12:46:37","slug":"on-gene-therapy-game-changer","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/on-gene-therapy-game-changer\/","title":{"rendered":"On gene therapy &#8211; Game-changer"},"content":{"rendered":"<p><strong>Source: <\/strong>This post on gene therapy is created based on the article <strong>\u201cgame changer\u201d<\/strong>, published in <strong>The Hindu<\/strong> on 13<sup>th<\/sup> December 2023.<\/p>\n<p><strong>Syllabus Topic: <\/strong>GS Paper 3 \u2013 Science and technology<\/p>\n<p><strong>News: <\/strong>Recently, the UK drug regulator and the U.S. FDA approved the gene therapies Casgevy and Lyfgenia for treating sickle cell disease in patients over 12 years.<\/p>\n<p>This marks a significant advancement in gene therapy using the CRISPR-Cas9 tool for diseases traditionally treated through bone marrow transplantation.<\/p>\n<p><a href=\"https:\/\/forumias.com\/blog\/lyfgenia-and-casgevy-u-s-fda-approves-gene-therapies-for-sickle-cell-disease\/\"><strong>Read more<\/strong><\/a><strong> about the technology<\/strong><\/p>\n<h2><strong>What are the advantages of Using CRISPR-Cas9<\/strong>?<\/h2>\n<p><strong>Patient&#8217;s Own Blood Cells<\/strong>: The use of the patient&#8217;s own blood cells for gene editing is a major advantage, potentially allowing treatment for a large number of patients without the need for donor matching.<\/p>\n<p><strong>Innovative Approach<\/strong>: The application of CRISPR-Cas9 in these therapies is a significant leap forward in genetic medicine, offering hope for many hereditary conditions.<\/p>\n<h2><strong>What are the challenges and considerations of using the CRISPR-Cas9?<\/strong><\/h2>\n<p><strong>Cost and Accessibility<\/strong>: Despite the potential, these treatments are expected to be extremely expensive, limiting their accessibility.<\/p>\n<p><strong>Hospital Capabilities<\/strong>: Only certain hospitals equipped with specific technologies can administer these therapies, further restricting access.<\/p>\n<p><strong>Safety and Efficacy Monitoring<\/strong>: Continuous monitoring for unintended genetic modifications and side effects is crucial due to the novel nature of these therapies.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source: This post on gene therapy is created based on the article \u201cgame changer\u201d, published in The Hindu on 13th December 2023. Syllabus Topic: GS Paper 3 \u2013 Science and technology News: Recently, the UK drug regulator and the U.S. FDA approved the gene therapies Casgevy and Lyfgenia for treating sickle cell disease in patients&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/on-gene-therapy-game-changer\/\">Continue reading <span class=\"screen-reader-text\">On gene therapy &#8211; Game-changer<\/span><\/a><\/p>\n","protected":false},"author":10320,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1230,9,31],"tags":[216,242,10498],"class_list":["post-273689","post","type-post","status-publish","format-standard","hentry","category-9-pm-daily-articles","category-public","category-science-technology","tag-gs-paper-3","tag-science-and-technology","tag-the-hindu","entry"],"jetpack_featured_media_url":"","views":{"total":73,"cached_at":"","cached_date":1703664128},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/273689","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10320"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=273689"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/273689\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=273689"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=273689"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=273689"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}