{"id":283138,"date":"2024-02-17T16:39:23","date_gmt":"2024-02-17T11:09:23","guid":{"rendered":"https:\/\/forumias.com\/blog\/?p=283138"},"modified":"2024-02-17T16:39:23","modified_gmt":"2024-02-17T11:09:23","slug":"diphtheria-who-guidelines-for-its-clinical-management","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/diphtheria-who-guidelines-for-its-clinical-management\/","title":{"rendered":"Diphtheria- WHO guidelines for its clinical management"},"content":{"rendered":"<p><strong>Source-<\/strong>This post on <strong>Diphtheria- WHO guidelines for its clinical management<\/strong> has been created based on the article &#8220;<strong><a href=\"https:\/\/www.financialexpress.com\/healthcare\/news-healthcare\/who-releases-guidelines-for-clinical-management-of-diphtheria-new-recommendations-on-antibiotics-usage-issued\/3393917\/\" target=\"_blank\" rel=\"noopener\">WHO releases guidelines for clinical management of diphtheria; New recommendations on antibiotics usage issued<\/a><\/strong>&#8221; published in &#8220;<strong>FE healthcare<\/strong>&#8221; on 14 February 2024.<\/p>\n<h2>Why in the news?<\/h2>\n<p>The World Health Organization (WHO) has recently published the guidelines on the clinical management of diphtheria.<\/p>\n<h2>About diphtheria<\/h2>\n<figure id=\"attachment_283145\" aria-describedby=\"caption-attachment-283145\" style=\"width: 500px\" class=\"wp-caption alignnone\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"wp-image-283145\" src=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2024\/02\/ias4sure.com-Diphtheria.jpg?resize=500%2C405&#038;ssl=1\" alt=\"Diphtheria\" width=\"500\" height=\"405\" srcset=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2024\/02\/ias4sure.com-Diphtheria.jpg?resize=300%2C243&amp;ssl=1 300w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2024\/02\/ias4sure.com-Diphtheria.jpg?w=660&amp;ssl=1 660w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><figcaption id=\"caption-attachment-283145\" class=\"wp-caption-text\">Source-The Hindu<\/figcaption><\/figure>\n<table style=\"height: 690px; width: 100%; border-collapse: collapse; border-style: solid;\">\n<tbody>\n<tr style=\"height: 30px;\">\n<td style=\"width: 12.7879%; height: 30px;\"><strong>Aspect<\/strong><\/td>\n<td style=\"width: 87.2121%; height: 30px;\"><strong>Details<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 30px;\">\n<td style=\"width: 12.7879%; height: 30px;\"><strong>Description<\/strong><\/td>\n<td style=\"width: 87.2121%; height: 30px;\">It is a serious<span style=\"color: #ff0000;\"> contagious bacterial infection<\/span> of the nose and throat.<\/td>\n<\/tr>\n<tr style=\"height: 60px;\">\n<td style=\"width: 12.7879%; height: 60px;\"><strong>Caused by<\/strong><\/td>\n<td style=\"width: 87.2121%; height: 60px;\">Strains of bacteria called<span style=\"color: #ff0000;\"> Corynebacterium diphtheriae<\/span> that make a toxin<\/td>\n<\/tr>\n<tr style=\"height: 90px;\">\n<td style=\"width: 12.7879%; height: 90px;\"><strong>Symptoms<\/strong><\/td>\n<td style=\"width: 87.2121%; height: 90px;\">A thick, gray membrane covering the <span style=\"color: #ff0000;\">throat and tonsils<\/span>,<span style=\"color: #ff0000;\"> sore throat<\/span> and hoarseness, <span style=\"color: #ff0000;\">swollen glands<\/span> (enlarged lymph nodes) in the neck and difficulty breathing etc<\/td>\n<\/tr>\n<tr style=\"height: 90px;\">\n<td style=\"width: 12.7879%; height: 90px;\"><strong>Transmission<\/strong><\/td>\n<td style=\"width: 87.2121%; height: 90px;\">1) It can spread from <span style=\"color: #ff0000;\">person to person<\/span>, usually through respiratory droplets, like from <span style=\"color: #ff0000;\">coughing or sneezing<\/span>.<br \/>\n2) People can also get sick from<span style=\"color: #ff0000;\"> touching infected open sores<\/span> or ulcers<\/td>\n<\/tr>\n<tr style=\"height: 180px;\">\n<td style=\"width: 12.7879%; height: 180px;\"><strong>Current treatment<\/strong><\/td>\n<td style=\"width: 87.2121%; height: 180px;\">1) It can be treated with medications but in advanced stages, the bacterial infection can damage the<span style=\"color: #ff0000;\"> heart<\/span>, <span style=\"color: #ff0000;\">kidneys<\/span> and <span style=\"color: #ff0000;\">nervous<\/span> system.<br \/>\n2) Neutralization of unbound<span style=\"color: #ff0000;\"> toxin with Diphtheria Antitoxin<\/span> (DAT).<br \/>\n3) <span style=\"color: #ff0000;\">Antibiotics<\/span> to prevent further bacterial growth.<br \/>\n4) <span style=\"color: #ff0000;\">Monitoring<\/span> and<span style=\"color: #ff0000;\"> supportive care<\/span> to prevent and treat complications, e.g. airway obstruction, myocarditis.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>What are WHO&#8217;s latest recommendation?<\/h2>\n<p>1) It has recommended the use of <span style=\"color: #ff0000;\">macrolide antibiotics<\/span> (azithromycin, erythromycin) in preference to <span style=\"color: #ff0000;\">penicillin antibiotics<\/span>.<br \/>\n2) It has recommended that routine sensitivity testing should not be performed <span style=\"color: #ff0000;\">prior<\/span> to administration of <span style=\"color: #ff0000;\">diphtheria antitoxin (DAT).<\/span><br \/>\n3) It has suggested an escalation in the dosage regimen for diphtheria antitoxin (DAT) based on <span style=\"color: #ff0000;\">disease severity.<span style=\"color: #333333;\"> It has <\/span><\/span>also opposed giving<span style=\"color: #ff0000;\">\u00a0fixed dose<\/span> for <span style=\"color: #ff0000;\">all<\/span> patients.<br \/>\n4)\u00a0 It has suggested to administer antibiotics <span style=\"color: #ff0000;\">alongside DAT<\/span><span style=\"color: #ff0000;\">. <span style=\"color: #333333;\">The antibiotics treatment should not be delayed.<\/span><\/span><\/p>\n<p>Read more about- <a href=\"https:\/\/forumias.com\/blog\/intensified-mission-indradhanush-imi-3-0\/#gsc.tab=0\" target=\"_blank\" rel=\"noopener\">Mission Indradhanush<\/a><\/p>\n<p><strong>UPSC Syllabus-Science &amp; technology.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source-This post on Diphtheria- WHO guidelines for its clinical management has been created based on the article &#8220;WHO releases guidelines for clinical management of diphtheria; New recommendations on antibiotics usage issued&#8221; published in &#8220;FE healthcare&#8221; on 14 February 2024. Why in the news? The World Health Organization (WHO) has recently published the guidelines on the&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/diphtheria-who-guidelines-for-its-clinical-management\/\">Continue reading <span class=\"screen-reader-text\">Diphtheria- WHO guidelines for its clinical management<\/span><\/a><\/p>\n","protected":false},"author":10374,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738],"tags":[11872],"class_list":["post-283138","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","tag-9pm-daily-factly","entry"],"jetpack_featured_media_url":"","views":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/283138","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10374"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=283138"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/283138\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=283138"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=283138"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=283138"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}