{"id":286190,"date":"2024-03-08T17:46:49","date_gmt":"2024-03-08T12:16:49","guid":{"rendered":"https:\/\/forumias.com\/blog\/?p=286190"},"modified":"2024-03-08T17:46:49","modified_gmt":"2024-03-08T12:16:49","slug":"penicillin-g-manufacturing-to-restart-in-india","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/penicillin-g-manufacturing-to-restart-in-india\/","title":{"rendered":"Penicillin G manufacturing to restart in India"},"content":{"rendered":"<p><strong>Source<\/strong>-This post on<strong> Penicillin G manufacturing in India<\/strong> has been created based on the article <a href=\"https:\/\/indianexpress.com\/article\/explained\/explained-health\/india-to-restart-penicillin-g-manufacture-why-it-stopped-9199850\/\" target=\"_blank\" rel=\"noopener\"><strong>&#8220;India to restart Penicillin G manufacture: why was it stopped, what changed now<\/strong><\/a>&#8221; published in &#8220;<strong>The Indian Express<\/strong>&#8221; on 7 March 2024.<\/p>\n<h2>Why in the news?<\/h2>\n<p>India has decided to resume the manufacturing of the common antibiotic Penicillin G after nearly 3 decades.<\/p>\n<h2>About Penicillin G<\/h2>\n<figure id=\"attachment_286201\" aria-describedby=\"caption-attachment-286201\" style=\"width: 400px\" class=\"wp-caption alignnone\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"wp-image-286201\" src=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2024\/03\/360_F_699905830_yv2mOEo6cVmbyhVZjFgtz5HQZhRpwK2k.jpg?resize=400%2C225&#038;ssl=1\" alt=\"Penicillin G\" width=\"400\" height=\"225\" srcset=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2024\/03\/360_F_699905830_yv2mOEo6cVmbyhVZjFgtz5HQZhRpwK2k.jpg?resize=300%2C169&amp;ssl=1 300w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2024\/03\/360_F_699905830_yv2mOEo6cVmbyhVZjFgtz5HQZhRpwK2k.jpg?w=639&amp;ssl=1 639w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><figcaption id=\"caption-attachment-286201\" class=\"wp-caption-text\">Source-Adobe Stock<\/figcaption><\/figure>\n<p>1) It is a medication used to manage and treat a wide range of infections. This is very effective against<span style=\"color: #ff0000;\"> gram-positive and gram-negative<\/span> cocci bacterial infections. For Ex- Susceptible bacterial infections in the stomach.<\/p>\n<p>2) It is the <span style=\"color: #ff0000;\">active pharmaceutical ingredient (API)<\/span> used in manufacturing several common antibiotics.<\/p>\n<h2>About Active Pharmaceutical Ingredients<\/h2>\n<p><strong>Description<\/strong>&#8211; These are the active ingredients contained in a medicine. It is that part of the medicine that produces the<span style=\"color: #ff0000;\"> intended therapeutic effects<\/span>. For\u00a0example, in a painkiller, the active ingredient relieves pain.<\/p>\n<p><strong>Quantity<\/strong>&#8211; A <span style=\"color: #ff0000;\">Small amount<\/span> of the API is required to produce the effect, and so the medicine contains only the required amount of the API.<\/p>\n<p><strong>Largest production<\/strong>&#8211; <span style=\"color: #ff0000;\">China<\/span> is one of the largest producers of Key Starting Material (KSM) and APIs in the world.<\/p>\n<h2>Why did penicillin manufacturing stop in India?<\/h2>\n<p>1) It was phased out of production because of <span style=\"color: #ff0000;\">subsidy-driven cheaper Chinese<\/span> products flooding the market.<\/p>\n<p>2) <span style=\"color: #ff0000;\">The Drug Prices Control Order<\/span> ensured that more companies went for cheaper imported products. The Drug Prices Control Order regulates the price of essential medicines in India.<\/p>\n<h2>What is a Production Linked Incentive (PLI) Scheme?<\/h2>\n<p><strong>Objective<\/strong>&#8211; To promote the <span style=\"color: #ff0000;\">domestic manufacturing<\/span> of APIs, drug intermediates and key starting materials (KSMs).<\/p>\n<p><strong>Incentive<\/strong>&#8211; The scheme envisages support of 20% for first four years, 15% for fifth year, and 5% for sixth year on eligible sales of<span style=\"color: #ff0000;\"> fermentation-based bulk drugs such as antibiotics, enzymes, and hormones such as insulin<\/span>.<\/p>\n<p><strong>Implementation<\/strong>&#8211; The scheme will be implemented through a <span style=\"color: #ff0000;\">Project Management Agency<\/span> (PMA) to be nominated by the Department of Pharmaceuticals.<\/p>\n<p><strong>NOTE<\/strong>&#8211; After PLI scheme, there has been a decline in the imports of APIs.<\/p>\n<p>Read more-<a href=\"https:\/\/forumias.com\/blog\/antimicrobial-resistance-amr-explained-pointwise\/#gsc.tab=0\" target=\"_blank\" rel=\"noopener\">Increasing Antimicrobial Resistance in India<\/a><\/p>\n<p><strong>UPSC Syllabus-Science &amp; technology<\/strong>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source-This post on Penicillin G manufacturing in India has been created based on the article &#8220;India to restart Penicillin G manufacture: why was it stopped, what changed now&#8221; published in &#8220;The Indian Express&#8221; on 7 March 2024. Why in the news? India has decided to resume the manufacturing of the common antibiotic Penicillin G after&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/penicillin-g-manufacturing-to-restart-in-india\/\">Continue reading <span class=\"screen-reader-text\">Penicillin G manufacturing to restart in India<\/span><\/a><\/p>\n","protected":false},"author":10374,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738],"tags":[11872],"class_list":["post-286190","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","tag-9pm-daily-factly","entry"],"jetpack_featured_media_url":"","views":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/286190","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10374"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=286190"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/286190\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=286190"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=286190"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=286190"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}