{"id":291559,"date":"2024-04-19T17:07:56","date_gmt":"2024-04-19T11:37:56","guid":{"rendered":"https:\/\/forumias.com\/blog\/?p=291559"},"modified":"2024-04-19T17:07:56","modified_gmt":"2024-04-19T11:37:56","slug":"randomised-control-trials-techniques-that-transformed-tb-care","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/randomised-control-trials-techniques-that-transformed-tb-care\/","title":{"rendered":"Randomised control trials- Techniques that transformed TB care"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong>Source\u2013<\/strong> This post on <strong>Randomised control trials technique transformed TB care<\/strong> is based on the article <strong><a href=\"https:\/\/epaper.thehindu.com\/ccidist-ws\/th\/th_delhi\/issues\/79839\/OPS\/GHDCMIVAS.1+GTVCMIVP4.1.html\" target=\"_blank\" rel=\"noopener\">&#8220;Randomised control trials: the technique that transformed TB care&#8221;<\/a> <\/strong>published in \u201cThe Hindu\u201d on 19th April 2024.<\/p>\n<h2 style=\"text-align: justify;\">Why in the News?<\/h2>\n<p style=\"text-align: justify;\">Clinical trials performed using the randomisation technique have been instrumental in shaping modern medicine.<\/p>\n<h2 style=\"text-align: justify;\">How randomisation technique transformed TB care<\/h2>\n<figure style=\"width: 500px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/th.bing.com\/th\/id\/OIP.1XpT4Yb6RKK0yzAVTnGoHQHaEK?w=500&amp;h=281&amp;rs=1&amp;pid=ImgDetMain\" alt=\"302 Randomised controlled trials and comparing groups \" width=\"500\" height=\"281\" \/><figcaption class=\"wp-caption-text\">Source: Quizlet<\/figcaption><\/figure>\n<p style=\"text-align: justify;\">1. Clinical trials utilizing randomization have profoundly impacted modern medicine by providing a reliable and impartial means to assess treatment efficacies.<\/p>\n<p style=\"text-align: justify;\">2. These trials are foundational to various medical advancements, such as <span style=\"color: #ff0000;\">understanding aspirin&#8217;s preventative role against heart attacks, crafting antiretroviral therapies for HIV, employing cognitive behavioral therapy for mental disorders, <\/span>and<span style=\"color: #ff0000;\"> developing the latest COVID-19 vaccines.<\/span><\/p>\n<p style=\"text-align: justify;\">3. <span style=\"color: #ff0000;\">Randomized controlled trials (RCTs)<\/span> were used to test streptomycin, marking it as the first effective antibiotic treatment against tuberculosis (TB). Sir Austin Bradford Hill is credited with the work.<\/p>\n<p style=\"text-align: justify;\">4. This transition changed TB management from a specialized surgical concern to a broadly accessible primary care matter.<\/p>\n<p style=\"text-align: justify;\">5. Beyond TB, Hill&#8217;s legacy continues with the <span style=\"color: #ff0000;\">&#8216;Bradford Hill Criteria,&#8217;<\/span> which are fundamental in modern epidemiology.<\/p>\n<p style=\"text-align: justify;\">These nine criteria <span style=\"color: #ff0000;\">strength, consistency, specificity, temporality, biological gradient, plausibility, coherence, experiment, and analogy<\/span> establish a structured approach to confirming causal relationships between specific factors and health outcomes.<\/p>\n<p style=\"text-align: justify;\">6. This framework has been instrumental in identifying alcohol as a <span style=\"color: #ff0000;\">risk factor for cardiovascular diseases and linking sugar-sweetened beverages with obesity.<\/span><\/p>\n<p style=\"text-align: justify;\">7. Hill\u2019s criteria were crucial in proving the connection between smoking and lung cancer, countering the misinformation spread by the tobacco industry.<\/p>\n<p style=\"text-align: justify;\">8. This research also influenced a major shift in public health policies and the general public\u2019s view on tobacco use.<\/p>\n<h2 style=\"text-align: justify;\">About the Randomised control trials technique<\/h2>\n<p style=\"text-align: justify;\">RCTs involve <span style=\"color: #ff0000;\">dividing a population into smaller groups<\/span>, in order to <span style=\"color: #ff0000;\">comparatively see the outcomes of an external stimulus<\/span>.<\/p>\n<p style=\"text-align: justify;\"><strong>For ex-<\/strong> If the aim of a study is to understand whether a free grains distribution scheme helped improve the nutrition levels among people living in a district, researchers will first create two groups within the population, and then put people into those groups randomly.<\/p>\n<p style=\"text-align: justify;\">One group (called the control group) does not receive the grains or the external stimulus, while the other group (treatment group) does. After a designated period of time, details of how both the groups are doing would be collected. In this way, the goal is to understand what the overall impact is of introducing something new could be.<\/p>\n<p>Read more: <a href=\"https:\/\/forumias.com\/blog\/explained-what-are-randomized-controlled-trials-how-do-they-work\/\" target=\"_blank\" rel=\"noopener\">What are randomized controlled trials, how do they work?<\/a><\/p>\n<p style=\"text-align: justify;\"><strong>UPSC Syllabus: Health<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source\u2013 This post on Randomised control trials technique transformed TB care is based on the article &#8220;Randomised control trials: the technique that transformed TB care&#8221; published in \u201cThe Hindu\u201d on 19th April 2024. Why in the News? Clinical trials performed using the randomisation technique have been instrumental in shaping modern medicine. How randomisation technique transformed&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/randomised-control-trials-techniques-that-transformed-tb-care\/\">Continue reading <span class=\"screen-reader-text\">Randomised control trials- Techniques that transformed TB care<\/span><\/a><\/p>\n","protected":false},"author":10366,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,957],"tags":[11872,10498],"class_list":["post-291559","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-health","tag-9pm-daily-factly","tag-the-hindu","entry"],"jetpack_featured_media_url":"","views":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/291559","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10366"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=291559"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/291559\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=291559"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=291559"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=291559"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}