{"id":295423,"date":"2024-05-13T14:07:34","date_gmt":"2024-05-13T08:37:34","guid":{"rendered":"https:\/\/forumias.com\/blog\/?p=295423"},"modified":"2024-05-13T14:07:34","modified_gmt":"2024-05-13T08:37:34","slug":"caenorhabditis-elegans-worm","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/caenorhabditis-elegans-worm\/","title":{"rendered":"Caenorhabditis elegans worm"},"content":{"rendered":"<p><strong>Source<\/strong>-This post on <strong>Research on Caenorhabditis elegans worm<\/strong> is based on the article <a href=\"https:\/\/epaper.thehindu.com\/ccidist-ws\/th\/th_delhi\/issues\/82998\/OPS\/G23CPRI3V.1+G08CPRIAE.1.html\" target=\"_blank\" rel=\"noopener\"><strong>&#8220;This worm develops food habits and its offspring \u2018inherit\u2019 them&#8221;<\/strong><\/a> published in <strong>\u201cThe Hindu\u201d<\/strong> on 12th May 2024.<\/p>\n<h2>Why in the News?<\/h2>\n<p>Researchers found that when Caenorhabditis elegans worms ate harmful bacteria, their offspring learned to avoid it for up to four generations.<\/p>\n<h2>About the <em>Caenorhabditis elegans <\/em>worm<\/h2>\n<figure style=\"width: 456px\" class=\"wp-caption aligncenter\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/epaper.thehindu.com\/ccidist-ws\/th\/th_delhi\/issues\/82998\/OPS\/Public\/G23CPRI3V.1%2BG08CPRIC9.1.jpg?resize=456%2C253&#038;ssl=1\" alt=\"Caenorhabditis elegans\" width=\"456\" height=\"253\" \/><figcaption class=\"wp-caption-text\">Source: The hindu<\/figcaption><\/figure>\n<table style=\"width: 100%; border-collapse: collapse; border-style: solid;\">\n<tbody>\n<tr>\n<td style=\"width: 27.7778%;\"><strong>About the ringworm<\/strong><\/td>\n<td style=\"width: 72.2222%;\">1. <em>Caenorhabditis elegans<\/em>\u00a0is a microscopic (~1 mm) nematode (roundworm) that normally lives in soil.<br \/>\n2. It has become one of the &#8220;model&#8221; organisms in biology.<br \/>\n3. It is found in &#8220;higher&#8221; animals like mice and humans.<br \/>\n<span class=\"TextRun SCXW105430460 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW105430460 BCX0\">4. It was the<\/span><\/span><span class=\"TextRun SCXW105430460 BCX0\" lang=\"EN-US\" style=\"color: #ff0000;\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW105430460 BCX0\"> first multicellular organism<\/span><\/span><span class=\"TextRun SCXW105430460 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW105430460 BCX0\"> to have its <\/span><\/span><span class=\"TextRun SCXW105430460 BCX0\" lang=\"EN-US\" style=\"color: #ff0000;\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW105430460 BCX0\">full genome sequenced, <span style=\"color: #333333;\">and<\/span><\/span><\/span><span class=\"TextRun SCXW105430460 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW105430460 BCX0\">\u00a0<\/span><\/span><span class=\"TextRun SCXW105430460 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW105430460 BCX0\"><span style=\"color: #ff0000;\">neural wiring mapped<\/span>.<\/span><\/span><span class=\"EOP SCXW105430460 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 27.7778%;\"><strong>Characteristics<\/strong><\/td>\n<td style=\"width: 72.2222%;\"><strong>1. Rapid Development:<\/strong> It grows from fertilized egg to a millimetre-long adult in <span style=\"color: #ff0000;\">merely 3\u20135 days.<\/span><br \/>\n<strong>2. Accessibility:<\/strong> It offers a <span style=\"color: #ff0000;\">compact lifecycle<\/span> which facilitates experimental manipulation and observation.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 27.7778%;\"><strong>Significance<\/strong><\/td>\n<td style=\"width: 72.2222%;\">It is widely utilized to delve into neuronal and molecular biology due to its simplicity and genetic tractability.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>About the research and its findings<\/h2>\n<p>1. Findings from C. elegans research have provided profound insights into <span style=\"color: #ff0000;\">human physiology and broader biological mechanisms.<\/span><\/p>\n<p><strong>2. Inheritance of Learned Behavior:<\/strong> Researchers unveiled a fascinating phenomenon wherein C. elegans inherit knowledge across generations.<\/p>\n<p><strong>3. Mechanism:<\/strong> After consuming disease-causing bacteria, the worms passed on the learned avoidance behaviour to their progeny for up to four generations, mediated by small RNA molecules (sRNA).<\/p>\n<p><strong>4. Role of sRNA:<\/strong> Pseudomonas vranovensis bacteria produce sRNA, altering the worm&#8217;s feeding behaviour.\u00a0sRNA is ingested by worms, influencing gene expression and behavior, a process known as RNA interference.<\/p>\n<p><strong>5. Implications and Speculation:<\/strong> These finding raises intriguing questions about the potential for similar transgenerational behavioural modifications in humans.<\/p>\n<p>It also provokes exploration into whether microbial RNA can influence human behavior and inheritance, potentially reshaping our understanding of genetics and behavior.<\/p>\n<p><strong>6. Scientific Legacy:<\/strong><\/p>\n<p><strong>a) Nobel Recognition:<\/strong> Contributions from studies on C. elegans were acknowledged with Nobel Prizes in 2002, 2006, and 2008.<\/p>\n<p><strong>b) Medical Relevance:<\/strong> Insights gained from C. elegans research have extended to human genetics and disease mechanisms, underscoring its indispensable role in scientific advancement.<\/p>\n<h2>About DNA and RNA<\/h2>\n<p>1. DNA and RNA are fundamental components of genetic information transfer within cells.<\/p>\n<p>2. DNA consists of two strands made of phosphate and deoxyribose sugar molecules, encodes genes, each providing instructions for protein synthesis.<\/p>\n<p>3. The DNA bases (A, T, C, G) form complementary pairs (A-T, C-G) to create a stable double helix structure.<\/p>\n<p>4. In contrast, RNA has ribose sugar units attached to bases (A, C, G, U). During transcription, a cell transcribes DNA gene sequences into messenger RNA (mRNA), where the base sequence (A-T, C-G) is transcribed into (U-A, G-C).<\/p>\n<p>5. This mRNA directs protein synthesis at ribosomes based on its sequence.<\/p>\n<p><strong>UPSC Syllabus: Science and technology<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source-This post on Research on Caenorhabditis elegans worm is based on the article &#8220;This worm develops food habits and its offspring \u2018inherit\u2019 them&#8221; published in \u201cThe Hindu\u201d on 12th May 2024. Why in the News? Researchers found that when Caenorhabditis elegans worms ate harmful bacteria, their offspring learned to avoid it for up to four&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/caenorhabditis-elegans-worm\/\">Continue reading <span class=\"screen-reader-text\">Caenorhabditis elegans worm<\/span><\/a><\/p>\n","protected":false},"author":10366,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738],"tags":[11872,10498],"class_list":["post-295423","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","tag-9pm-daily-factly","tag-the-hindu","entry"],"jetpack_featured_media_url":"","views":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/295423","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10366"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=295423"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/295423\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=295423"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=295423"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=295423"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}