{"id":306858,"date":"2024-08-09T19:12:24","date_gmt":"2024-08-09T13:42:24","guid":{"rendered":"https:\/\/forumias.com\/blog\/?p=306858"},"modified":"2024-08-09T19:12:24","modified_gmt":"2024-08-09T13:42:24","slug":"dna-profiling","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/dna-profiling\/","title":{"rendered":"DNA Profiling"},"content":{"rendered":"<p><strong>Source-<\/strong> This post on <strong>DNA Profiling\u00a0<\/strong>has been created based on the article <a href=\"https:\/\/epaper.thehindu.com\/ccidist-ws\/th\/th_delhi\/issues\/94368\/OPS\/GA6D62CBI.1+GEVD62D9H.1.html\" target=\"_blank\" rel=\"noopener\">&#8220;DNA profiling and its value in establishing guilt or innocence&#8221;<\/a>\u00a0published in \u201c<strong>The Hindu\u201d<\/strong> on 9 August 2024.<\/p>\n<h2>Why in News?<\/h2>\n<p>In mid-June, the Madras High Court overturned the conviction of a man in a POCSO rape case, citing insufficient proof by the prosecution. The court questioned the sole reliance on DNA evidence for establishing guilt, noting the victim&#8217;s false accusation as a key factor in the wrongful conviction. This has increased the focus on the process of DNA profiling.<\/p>\n<h2>What is DNA?<\/h2>\n<p>1. DNA stands for Deoxyribonucleic Acid, which is the genetic material present in the nucleus of almost all cells in living organisms.<\/p>\n<p>2.\u00a0 It carries information that determines the internal organization, physical characteristics, and physiological functions of the body.<\/p>\n<p>3. DNA is made up of four nucleotide bases: Adenine (A), Guanine (G), Thymine (T), and Cytosine (C), arranged in a double-helix structure.<\/p>\n<h2>About DNA Profiling<\/h2>\n<p>1. DNA profiling is a method used to identify individuals based on their unique DNA sequences.<\/p>\n<p>2.\u00a0 Although 99.9% of human DNA is identical, the remaining 0.1% contains variations that can be used to create a DNA profile.<\/p>\n<p>3.\u00a0 Specific locations in this 0.1% are examined, focusing on Short Tandem Repeats (STRs), which are repetitive sequences of DNA that vary from person to person.<\/p>\n<h2>About Process of DNA Profiling<\/h2>\n<figure style=\"width: 301px\" class=\"wp-caption aligncenter\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/www.researchgate.net\/profile\/Nwawuba-Stanley\/publication\/356777328\/figure\/fig3\/AS%3A1103410698944524%401640085019608\/Steps-for-DNA-profiling-using-restriction-length-polymorphism-42.png?resize=301%2C209&#038;ssl=1\" alt=\"Steps for DNA profiling using restriction length polymorphism. \" width=\"301\" height=\"209\" \/><figcaption class=\"wp-caption-text\">Source: Researchgate<\/figcaption><\/figure>\n<table style=\"height: 329px; width: 100%; border-collapse: collapse; border-style: solid;\">\n<tbody>\n<tr style=\"height: 29px;\">\n<td style=\"width: 27.9176%; height: 29px;\"><strong>Process\u00a0<\/strong><\/td>\n<td style=\"width: 72.0824%; height: 29px;\"><strong>Description\u00a0<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 150px;\">\n<td style=\"width: 27.9176%; height: 150px;\"><strong>Sample Collection<\/strong><\/td>\n<td style=\"width: 72.0824%; height: 150px;\">1. DNA can be collected from various biological materials like blood, saliva, semen, hair, or skin cells.<br \/>\n2. The process of collecting, storing, and transporting DNA samples is crucial to avoid contamination and ensure the accuracy of the results.<\/td>\n<\/tr>\n<tr style=\"height: 150px;\">\n<td style=\"width: 27.9176%; height: 150px;\"><strong>Laboratory Analysis<\/strong><\/td>\n<td style=\"width: 72.0824%; height: 150px;\">1. DNA profiling involves several steps: isolating DNA from the sample, amplifying specific genetic markers, and analyzing these markers to create a DNA profile.<br \/>\n2. The key steps are isolation, purification, amplification, visualization, genotyping, and statistical analysis.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>How reliabile is DNA Profiling<\/h2>\n<p>1. DNA profiling is a powerful tool in forensic science, but it is not infallible. The process is based on probability, and various factors like sample contamination, degradation, or mishandling can affect the results.<\/p>\n<p>2. The reliability of DNA evidence also depends on the quality of the sample and the expertise of the laboratory performing the analysis.<\/p>\n<h2>DNA Profiling in Criminal Cases<\/h2>\n<p><strong>1. Role in Establishing Guilt or Innocence:<\/strong> DNA evidence can be critical in criminal investigations, helping to identify or exclude suspects. However, DNA evidence alone may not be conclusive.<\/p>\n<p>2. Courts often require additional evidence to corroborate DNA findings before reaching a verdict.<\/p>\n<p>3. In legal cases, the probative value of DNA evidence can vary. Courts may treat DNA evidence as strong, but not absolute, and it must be weighed alongside other evidence.<\/p>\n<p>4. The absence of DNA evidence does not automatically imply innocence or guilt; other evidence may still be critical to the case.<\/p>\n<p><strong>UPSC Syllabus: Science and technology<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source- This post on DNA Profiling\u00a0has been created based on the article &#8220;DNA profiling and its value in establishing guilt or innocence&#8221;\u00a0published in \u201cThe Hindu\u201d on 9 August 2024. Why in News? In mid-June, the Madras High Court overturned the conviction of a man in a POCSO rape case, citing insufficient proof by the prosecution.&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/dna-profiling\/\">Continue reading <span class=\"screen-reader-text\">DNA Profiling<\/span><\/a><\/p>\n","protected":false},"author":10366,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738],"tags":[11872,10498],"class_list":["post-306858","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","tag-9pm-daily-factly","tag-the-hindu","entry"],"jetpack_featured_media_url":"","views":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/306858","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10366"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=306858"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/306858\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=306858"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=306858"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=306858"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}