{"id":313765,"date":"2024-10-19T18:48:55","date_gmt":"2024-10-19T13:18:55","guid":{"rendered":"https:\/\/forumias.com\/blog\/?p=313765"},"modified":"2024-12-12T12:14:55","modified_gmt":"2024-12-12T06:44:55","slug":"smart-insulin-to-control-blood-sugar-level","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/smart-insulin-to-control-blood-sugar-level\/","title":{"rendered":"Smart insulin to control blood sugar level"},"content":{"rendered":"<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-319520\" src=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2024\/10\/Smart-Insulin-to-Control-Blood-Sugar-Level.png?resize=740%2C493&#038;ssl=1\" alt=\"Smart Insulin to Control Blood Sugar Level\" width=\"740\" height=\"493\" srcset=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2024\/10\/Smart-Insulin-to-Control-Blood-Sugar-Level.png?resize=300%2C200&amp;ssl=1 300w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2024\/10\/Smart-Insulin-to-Control-Blood-Sugar-Level.png?resize=1024%2C682&amp;ssl=1 1024w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2024\/10\/Smart-Insulin-to-Control-Blood-Sugar-Level.png?resize=768%2C512&amp;ssl=1 768w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2024\/10\/Smart-Insulin-to-Control-Blood-Sugar-Level.png?w=1280&amp;ssl=1 1280w\" sizes=\"auto, (max-width: 740px) 100vw, 740px\" \/><\/p>\n<p><strong>Source:<\/strong> This post on Smart insulin to control blood sugar level has been created based on the article <a href=\"https:\/\/indianexpress.com\/article\/explained\/explained-health\/how-smart-insulin-promises-to-revolutionise-diabetes-treatment-9627565\/\" target=\"_blank\" rel=\"noopener\">&#8220;<span style=\"background-color: var(--global--color-background); color: var(--global--color-primary); font-family: var(--global--font-secondary); font-size: var(--global--font-size-base);\">How \u2018smart insulin\u2019 promises to revolutionise diabetes treatment&#8221; <\/span><\/a><span style=\"background-color: var(--global--color-background); color: var(--global--color-primary); font-family: var(--global--font-secondary); font-size: var(--global--font-size-base);\">published in Indian Express on 18th October 2024.<\/span><\/p>\n<h2>Why in news?<\/h2>\n<p>Recently, an international team of scientists from Denmark, the UK, Czechia, and the University of Bristol has engineered a \u201csmart\u201d insulin called NNC2215 that responds automatically to blood sugar changes. <strong>Smart Insulin to Control Blood Sugar Level.<\/strong><\/p>\n<h2>How It Works:<\/h2>\n<p>i) NNC2215 consists of a ring-shaped structure and a glucoside molecule. The glucoside binds to the ring when low blood glucose, keeping the insulin inactive.<\/p>\n<p>ii) As glucose levels rise, glucose replaces the glucoside, activating the insulin to lower blood sugar.<\/p>\n<h2>Potential Benefits<\/h2>\n<p><strong>Easier Management:<\/strong> This smart insulin could simplify blood sugar management, reducing the need for constant monitoring and improving the quality of life for millions of people dependent on insulin therapy.<\/p>\n<p><strong>Effectiveness in Studies:<\/strong> NNC2215 has shown to be as effective as human insulin in controlling blood glucose in animal tests (rats and pigs), and human trials are expected soon.<\/p>\n<h2>Challenges in Insulin Management<\/h2>\n<p><strong>Constant Monitoring:<\/strong> Patients with diabetes need to continuously monitor their blood sugar levels and adjust insulin doses, as blood glucose levels fluctuate throughout the day.<\/p>\n<p><strong>Risk of Overdosing:<\/strong> Overdosing on insulin can cause blood glucose levels to drop dangerously low, which can be life-threatening.<\/p>\n<h2>Current Limitations and Future Improvements<\/h2>\n<p><strong>Abrupt Activation:<\/strong> One limitation of NNC2215 is that it activates only after a significant spike in glucose, leading to a sudden insulin release.<\/p>\n<p><strong>Ongoing Refinement:<\/strong> Scientists are working to improve the insulin molecule so that it activates more gradually, allowing insulin levels to rise slowly for better glucose control.<\/p>\n<h2>Current Insulin Therapies<\/h2>\n<p><strong>Traditional Methods:<\/strong> Insulin therapies involve administering synthetic insulin, but keeping blood sugar levels stable remains a challenge.<\/p>\n<p><strong>Glucose-Sensitive Insulin:<\/strong> Some advanced therapies rely on insulin being stored in the body and released based on glucose levels detected by sensors.<\/p>\n<p><strong>UPSC Syllabus: Science and technology\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source: This post on Smart insulin to control blood sugar level has been created based on the article &#8220;How \u2018smart insulin\u2019 promises to revolutionise diabetes treatment&#8221; published in Indian Express on 18th October 2024. Why in news? Recently, an international team of scientists from Denmark, the UK, Czechia, and the University of Bristol has engineered&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/smart-insulin-to-control-blood-sugar-level\/\">Continue reading <span class=\"screen-reader-text\">Smart insulin to control blood sugar level<\/span><\/a><\/p>\n","protected":false},"author":10366,"featured_media":319520,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738],"tags":[11872],"class_list":["post-313765","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","tag-9pm-daily-factly","entry"],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2024\/10\/Smart-Insulin-to-Control-Blood-Sugar-Level.png?fit=1280%2C853&ssl=1","views":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/313765","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10366"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=313765"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/313765\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media\/319520"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=313765"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=313765"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=313765"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}