{"id":324776,"date":"2025-01-27T14:31:25","date_gmt":"2025-01-27T09:01:25","guid":{"rendered":"https:\/\/forumias.com\/blog\/?p=324776"},"modified":"2025-01-27T14:31:25","modified_gmt":"2025-01-27T09:01:25","slug":"stargardt-disease","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/stargardt-disease\/","title":{"rendered":"Stargardt disease"},"content":{"rendered":"<p><strong>News<\/strong>&#8211; Researchers from Switzerland have announced the development of a gene-editing technique that may potentially aid in the treatment of Stargardt disease.<\/p>\n<h2>About Stargardt Disease<\/h2>\n<ul>\n<li>It is a <em>rare inherited genetic disorder<\/em> that leads to progressive vision loss, especially in children and young adults.<\/li>\n<li><strong>Cause<\/strong>: The disease is caused by <em>mutations in the ABCA4 gene<\/em>, which disrupts the body\u2019s ability to process <em>Vitamin A<\/em> properly. This leads to the accumulation of <em>lipofuscin<\/em>, a fatty substance that builds up on the macula\u2014the central part of the retina responsible for sharp, central vision.<\/li>\n<li><strong>Bilateral<\/strong>: Stargardt disease typically <em>affects both eyes<\/em> (bilateral), resulting in the gradual loss of central visual acuity in both eyes.<\/li>\n<li><strong>No Cure<\/strong>: There is currently no cure or effective treatment for Stargardt disease, though research continues to explore potential therapies.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>News&#8211; Researchers from Switzerland have announced the development of a gene-editing technique that may potentially aid in the treatment of Stargardt disease. About Stargardt Disease It is a rare inherited genetic disorder that leads to progressive vision loss, especially in children and young adults. Cause: The disease is caused by mutations in the ABCA4 gene,&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/stargardt-disease\/\">Continue reading <span class=\"screen-reader-text\">Stargardt disease<\/span><\/a><\/p>\n","protected":false},"author":10367,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738,12039],"tags":[11872],"class_list":["post-324776","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","category-knolls","tag-9pm-daily-factly","entry"],"jetpack_featured_media_url":"","views":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/324776","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10367"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=324776"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/324776\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=324776"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=324776"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=324776"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}