{"id":332331,"date":"2025-04-09T18:23:06","date_gmt":"2025-04-09T12:53:06","guid":{"rendered":"https:\/\/forumias.com\/blog\/?p=332331"},"modified":"2025-04-11T18:51:57","modified_gmt":"2025-04-11T13:21:57","slug":"de-extinction-of-dire-wolf","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/de-extinction-of-dire-wolf\/","title":{"rendered":"De-Extinction of Dire Wolf"},"content":{"rendered":"<p><strong>News:<\/strong> In a groundbreaking achievement, scientists have successfully revived the <strong>dire wolf<\/strong>, an ancient species that went <strong>extinct<\/strong> nearly 12,500 years ago, using <strong>cutting-edge genetic engineering techniques by Colossal Biosciences<\/strong>. <strong>De-Extinction of Dire Wolf.<\/strong><\/p>\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\" wp-image-332590 aligncenter\" src=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/04\/De-Extinction-of-Dire-Wolf.png?resize=531%2C352&#038;ssl=1\" alt=\"De-Extinction of Dire Wolf\" width=\"531\" height=\"352\" srcset=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/04\/De-Extinction-of-Dire-Wolf.png?resize=300%2C199&amp;ssl=1 300w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/04\/De-Extinction-of-Dire-Wolf.png?resize=1024%2C680&amp;ssl=1 1024w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/04\/De-Extinction-of-Dire-Wolf.png?resize=768%2C510&amp;ssl=1 768w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/04\/De-Extinction-of-Dire-Wolf.png?w=1280&amp;ssl=1 1280w\" sizes=\"auto, (max-width: 531px) 100vw, 531px\" \/><\/p>\n<h2>About De-Extinction<\/h2>\n<ul>\n<li>De-extinction, also known as resurrection biology or species revivalism, is the process of recreating extinct species or organisms using biotechnology, aiming to bring them back to life.<\/li>\n<\/ul>\n<h2>About Dire Wolf (Aenocyon dirus)<\/h2>\n<ul>\n<li>Habitat and Distribution: They were large <strong>canines<\/strong> that dominated the <strong>grasslands and forest<\/strong>sof <strong>southern Canada and the US<\/strong>.<\/li>\n<li>They resembled the <strong>grey\/ gray wolves (Canis lupus) of today<\/strong> but were <strong>larger, with white coats<\/strong>.<\/li>\n<li>A dire wolf could be <strong>5 feet tall<\/strong>, more than <strong>6 feet in length<\/strong>, and weigh <strong>up to 68 kg.<\/strong><\/li>\n<\/ul>\n<h2>Science behind De-Extinction Process of Dire Wolf<\/h2>\n<ul>\n<li>The dire wolf genome was <strong>extracted from two ancient samples<\/strong> preserved in a American museum of natural history.<\/li>\n<li>Colossal\u2019s dire wolf work <strong>took a less invasive approach<\/strong> (than cloning), isolating cells from the blood (not from a tissue sample) of a grey wolf.<\/li>\n<li>These cells are known as <strong>endothelial progenitor cells (EPCs),<\/strong> which form the lining of blood vessels.<\/li>\n<li>The scientists then <strong>rewrote the 14 key genes<\/strong> in the cell\u2019s nucleus to match those of the dire wolf <strong>using CRISPR<\/strong>.<\/li>\n<li>No ancient dire wolf DNA was actually spliced into the gray wolf\u2019s genome.<\/li>\n<li>The edited nucleus was then transferred into a de-nucleated ovum which was allowed to develop into embryos in the lab.<\/li>\n<li>When ready, embryos were transferred to surrogates, also domestic dogs, and 62 days later the genetically engineered pups were born.<\/li>\n<li>These \u201cdire wolves\u201d will become the <strong>second species on the planet<\/strong> to be brought back to life.\n<ul>\n<li>The <strong>first<\/strong> was the <strong>bucardo<\/strong>, a <strong>mountain goat from the Pyrenees, Europe.<\/strong><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>News: In a groundbreaking achievement, scientists have successfully revived the dire wolf, an ancient species that went extinct nearly 12,500 years ago, using cutting-edge genetic engineering techniques by Colossal Biosciences. De-Extinction of Dire Wolf. About De-Extinction De-extinction, also known as resurrection biology or species revivalism, is the process of recreating extinct species or organisms using&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/de-extinction-of-dire-wolf\/\">Continue reading <span class=\"screen-reader-text\">De-Extinction of Dire Wolf<\/span><\/a><\/p>\n","protected":false},"author":10393,"featured_media":332590,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738,12056],"tags":[11872],"class_list":["post-332331","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","category-knolls-daily-factly-articles","tag-9pm-daily-factly","entry"],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/04\/De-Extinction-of-Dire-Wolf.png?fit=1280%2C850&ssl=1","views":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/332331","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10393"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=332331"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/332331\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media\/332590"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=332331"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=332331"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=332331"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}