{"id":337482,"date":"2025-05-20T18:30:23","date_gmt":"2025-05-20T13:00:23","guid":{"rendered":"https:\/\/forumias.com\/blog\/?p=337482"},"modified":"2025-05-28T18:03:48","modified_gmt":"2025-05-28T12:33:48","slug":"a-to-i-mrna-editing-in-animals","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/a-to-i-mrna-editing-in-animals\/","title":{"rendered":"A-to-I mRNA Editing in Animals"},"content":{"rendered":"<p><strong>News: <\/strong>Researchers from China recently reported that it\u2019s hard to make sense of the widespread persistence of <strong>A-to-I mRNA editing in animals.<\/strong><\/p>\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\" wp-image-338555 aligncenter\" src=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/05\/A-to-I-mRNA-Editing-in-Animals.png?resize=514%2C341&#038;ssl=1\" alt=\"A-to-I mRNA Editing in Animals\" width=\"514\" height=\"341\" srcset=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/05\/A-to-I-mRNA-Editing-in-Animals.png?resize=300%2C199&amp;ssl=1 300w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/05\/A-to-I-mRNA-Editing-in-Animals.png?resize=1024%2C680&amp;ssl=1 1024w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/05\/A-to-I-mRNA-Editing-in-Animals.png?resize=768%2C510&amp;ssl=1 768w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/05\/A-to-I-mRNA-Editing-in-Animals.png?w=1280&amp;ssl=1 1280w\" sizes=\"auto, (max-width: 514px) 100vw, 514px\" \/><\/p>\n<h2>About A-to-I mRNA Editing in Animals<\/h2>\n<ul>\n<li><strong>mRNA<\/strong>: Our cells use DNA as a guide to make proteins. First, they copy DNA into messenger RNA (mRNA).<\/li>\n<li><strong>A-to-I editing:<\/strong> This is a process where the letter adenosine (A) in mRNA is changed to inosine (I) by special enzymes called ADARs.\n<ul>\n<li>The cell reads inosine as guanine (G), which can change the protein being made.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><strong>Importance<\/strong><\/p>\n<ul>\n<li>It helps the cell make different versions of proteins without changing the DNA.<\/li>\n<li>It can remove early stop signals, allowing full proteins to be made.<\/li>\n<li>It helps the cell adapt to different conditions or stages of life.<\/li>\n<\/ul>\n<p><strong>Latest<\/strong> <strong>Discovery<\/strong><\/p>\n<ul>\n<li><strong>Fungal Discovery<\/strong>: Scientists found that the fungus edits over 26,000 mRNA sites during reproduction, not during normal growth.<\/li>\n<li><strong>Development Role<\/strong>: This editing fixes early stop signals in key genes, helping the fungus develop and reproduce properly.<\/li>\n<li><strong>Stress Adaptation<\/strong>: Some genes work better unedited under stress, showing the fungus edits only when needed for survival.<\/li>\n<\/ul>\n<p><strong>Association with Humans: <\/strong>Yes, A-to-I editing is common in humans:<\/p>\n<ul>\n<li><strong>In the brain<\/strong>: It helps with brain growth, memory, and learning.<\/li>\n<li><strong>In the immune system<\/strong>: It helps fight infections and control inflammation.<\/li>\n<li><strong>Health Implications<\/strong>:\n<ul>\n<li><strong>Health Risks<\/strong>: Faulty editing is linked to epilepsy and certain cancers.<\/li>\n<li><strong>Therapeutic Potential<\/strong>: Understanding this process can lead to new treatments and improve gene-editing technologies.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>News: Researchers from China recently reported that it\u2019s hard to make sense of the widespread persistence of A-to-I mRNA editing in animals. About A-to-I mRNA Editing in Animals mRNA: Our cells use DNA as a guide to make proteins. First, they copy DNA into messenger RNA (mRNA). A-to-I editing: This is a process where the&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/a-to-i-mrna-editing-in-animals\/\">Continue reading <span class=\"screen-reader-text\">A-to-I mRNA Editing in Animals<\/span><\/a><\/p>\n","protected":false},"author":10393,"featured_media":338555,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738,12039],"tags":[11872],"class_list":["post-337482","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","category-knolls","tag-9pm-daily-factly","entry"],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/05\/A-to-I-mRNA-Editing-in-Animals.png?fit=1280%2C850&ssl=1","views":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/337482","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10393"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=337482"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/337482\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media\/338555"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=337482"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=337482"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=337482"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}