{"id":351183,"date":"2025-12-03T11:52:38","date_gmt":"2025-12-03T06:22:38","guid":{"rendered":"https:\/\/forumias.com\/blog\/?p=351183"},"modified":"2025-12-03T11:52:38","modified_gmt":"2025-12-03T06:22:38","slug":"glp-1-agonists","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/glp-1-agonists\/","title":{"rendered":"GLP-1 Agonists"},"content":{"rendered":"<p><strong>News<\/strong>: The WHO has issued its first guideline on GLP-1 therapies, conditionally recommending them for long-term obesity treatment worldwide.<\/p>\n<h2>About GLP-1 Agonists<\/h2>\n<figure id=\"attachment_351184\" aria-describedby=\"caption-attachment-351184\" style=\"width: 358px\" class=\"wp-caption aligncenter\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"wp-image-351184 \" src=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/12\/Source-What-Is-Biotechnology.jpg?resize=358%2C272&#038;ssl=1\" alt=\"GLP-1 Agonists\" width=\"358\" height=\"272\" srcset=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/12\/Source-What-Is-Biotechnology.jpg?resize=300%2C228&amp;ssl=1 300w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/12\/Source-What-Is-Biotechnology.jpg?resize=768%2C583&amp;ssl=1 768w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2025\/12\/Source-What-Is-Biotechnology.jpg?w=935&amp;ssl=1 935w\" sizes=\"auto, (max-width: 358px) 100vw, 358px\" \/><figcaption id=\"caption-attachment-351184\" class=\"wp-caption-text\">Source &#8211; What Is Biotechnology<\/figcaption><\/figure>\n<ul>\n<li>GLP-1 drugs, also called GLP-1 agonists, are shortened names for <strong>glucagon-like peptide-1<\/strong> <strong>receptor agonists.<\/strong><\/li>\n<li>They <strong>mimic<\/strong> the <strong>GLP-1 hormone<\/strong> that is <strong>naturally released in the gastrointestinal tract<\/strong> in <strong>response to eating<\/strong>.<\/li>\n<li><strong>Function: <\/strong>They help <strong>lower blood sugar and support weight loss<\/strong> by <strong>increasing insulin release<\/strong>, <strong>slowing stomach emptying<\/strong> and <strong>reducing appetite.<\/strong><\/li>\n<li><strong>Mechanism<\/strong>\n<ul>\n<li>They mimic the natural hormone GLP-1, which <strong>signals the pancreas to release insulin after meals<\/strong> and <strong>suppresses excess glucagon<\/strong>.<\/li>\n<li>They also <strong>act on the brain<\/strong> to <strong>reduce hunger<\/strong> and on the <strong>gut to slow digestion,<\/strong> leading to better glucose control and reduced calorie intake.<\/li>\n<\/ul>\n<\/li>\n<li><strong>Side effects<\/strong>\n<ul>\n<li>It can cause <strong>gastrointestinal issues<\/strong> such as <strong>nausea, vomiting, diarrhea or constipation.<\/strong><\/li>\n<li>They may also cause <strong>\u201c<\/strong><strong>Ozempic face,<\/strong><strong>\u201d<\/strong> which appears as <strong>hollow or sagging skin,<\/strong> with sunken cheeks or eyes, especially when weight loss happens quickly.<\/li>\n<li>GLP-1 drugs can cause problems like <strong>pancreatitis (inflammation of the pancreas)<\/strong>, <strong>gastroparesis or bowel obstruction<\/strong>, and <strong>gallbladder or bile-duct issues<\/strong>.<\/li>\n<\/ul>\n<\/li>\n<li><strong>WHO recommendations<\/strong>\n<ul>\n<li>WHO conditionally recommends GLP-1 drugs for long-term obesity treatment in adults with a <strong>BMI of 30 or higher, except pregnant women<\/strong>.<\/li>\n<li>The guideline recommends <strong>three GLP-1 medicines:<\/strong> <strong>semaglutide, tirzepatide<\/strong> and an older medicine from the same class <strong>called liraglutide.<\/strong><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>News: The WHO has issued its first guideline on GLP-1 therapies, conditionally recommending them for long-term obesity treatment worldwide. About GLP-1 Agonists GLP-1 drugs, also called GLP-1 agonists, are shortened names for glucagon-like peptide-1 receptor agonists. They mimic the GLP-1 hormone that is naturally released in the gastrointestinal tract in response to eating. Function: They&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/glp-1-agonists\/\">Continue reading <span class=\"screen-reader-text\">GLP-1 Agonists<\/span><\/a><\/p>\n","protected":false},"author":10393,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738,12039],"tags":[11872],"class_list":["post-351183","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","category-knolls","tag-9pm-daily-factly","entry"],"jetpack_featured_media_url":"","views":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/351183","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10393"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=351183"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/351183\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=351183"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=351183"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=351183"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}