{"id":367661,"date":"2026-07-17T16:56:35","date_gmt":"2026-07-17T11:26:35","guid":{"rendered":"https:\/\/forumias.com\/blog\/?p=367661"},"modified":"2026-07-17T16:56:35","modified_gmt":"2026-07-17T11:26:35","slug":"melatonin","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/melatonin\/","title":{"rendered":"Melatonin"},"content":{"rendered":"<div class=\"content-box-green\">\n<p><strong>News:<\/strong> A new study suggests that melatonin may help reduce chronic muscle and joint pain, besides its well-known role in regulating sleep.<\/p>\n<\/div>\n<h2 class=\"red-h2-box\"><strong>About Melatonin<\/strong><\/h2>\n<figure id=\"attachment_367667\" aria-describedby=\"caption-attachment-367667\" style=\"width: 287px\" class=\"wp-caption aligncenter\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-367667\" src=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2026\/07\/Source-Cleveland-Clinic.jpg?resize=287%2C300&#038;ssl=1\" alt=\"Melatonin\" width=\"287\" height=\"300\" srcset=\"https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2026\/07\/Source-Cleveland-Clinic.jpg?resize=287%2C300&amp;ssl=1 287w, https:\/\/i0.wp.com\/forumias.com\/blog\/wp-content\/uploads\/2026\/07\/Source-Cleveland-Clinic.jpg?w=756&amp;ssl=1 756w\" sizes=\"auto, (max-width: 287px) 100vw, 287px\" \/><figcaption id=\"caption-attachment-367667\" class=\"wp-caption-text\">Source &#8211; Cleveland Clinic<\/figcaption><\/figure>\n<ul>\n<li><strong>Melatonin<\/strong>\u00a0is a <strong>naturally occurring indoleamine hormone<\/strong> primarily <strong>responsible for regulating the human body&#8217;s circadian rhythm and sleep-wake cycles.<\/strong><\/li>\n<li><strong>Natural Origin :<\/strong> Melatonin is naturally <strong>secreted by the pineal gland<\/strong> in the brain.\n<ul>\n<li>Its <strong>production increases in darkness and decreases when the body is exposed to light.<\/strong><\/li>\n<\/ul>\n<\/li>\n<li><strong>Synthetic:<\/strong> Melatonin can <strong>also be produced synthetically in laboratories<\/strong> and sold as a dietary supplement, which is <strong>known as exogenous melatonin<\/strong>.<\/li>\n<li><strong>Functions of Melatonin:<\/strong>\n<ul>\n<li><strong>Sleep Regulation:<\/strong> Melatonin regulates the body&#8217;s sleep-wake cycle by increasing in darkness and preparing the body for sleep.\n<ul>\n<li><strong>It is widely used to treat insomnia and jet lag.<\/strong><\/li>\n<\/ul>\n<\/li>\n<li><strong>Pain Regulation:<\/strong> Melatonin may <strong>reduce chronic muscle and joint pain by dampening pain signals in the brain and spinal cord<\/strong>, reducing inflammation, calming overactive nerves, and protecting cells from oxidative stress.<\/li>\n<li><strong>Antioxidative and Neuroprotective Properties:<\/strong> Nano-formulated melatonin showed <strong>enhanced antioxidative and neuroprotective properties<\/strong> because of its sustained release and improved bioavailability.<\/li>\n<li><strong><strong>Mitophagy Regulation: <\/strong><\/strong>Melatonin <strong>improves mitophagy<\/strong>, a process that<strong> removes unhealthy mitochondria from cells<\/strong>, and <strong>enhances mitochondrial biogenesis, which helps reduce oxidative stress<strong><br \/>\n<\/strong><\/strong><\/li>\n<li><strong>Role in Parkinson&#8217;s Disease:<\/strong> Nano-formulated <strong>melatonin showed enhanced neuroprotective effects and reduced oxidative stress in Parkinson&#8217;s disease models,<\/strong> indicating its potential as a therapeutic candidate.<\/li>\n<\/ul>\n<\/li>\n<li><strong>Concern:<\/strong> Melatonin provides only modest benefits based on current evidence and <strong>may cause side effects<\/strong> such as <strong>daytime sleepiness, dizziness, headaches, nausea, hormonal changes, and mood swings.<\/strong><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>News: A new study suggests that melatonin may help reduce chronic muscle and joint pain, besides its well-known role in regulating sleep. About Melatonin Melatonin\u00a0is a naturally occurring indoleamine hormone primarily responsible for regulating the human body&#8217;s circadian rhythm and sleep-wake cycles. Natural Origin : Melatonin is naturally secreted by the pineal gland in the&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/melatonin\/\">Continue reading <span class=\"screen-reader-text\">Melatonin<\/span><\/a><\/p>\n","protected":false},"author":10401,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1566,1738,12039],"tags":[11872],"class_list":["post-367661","post","type-post","status-publish","format-standard","hentry","category-daily-factly-articles","category-science-and-technology-daily-factly-articles","category-knolls","tag-9pm-daily-factly","entry"],"jetpack_featured_media_url":"","views":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/367661","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10401"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=367661"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/367661\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=367661"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=367661"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=367661"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}