{"id":66390,"date":"2020-10-13T13:08:19","date_gmt":"2020-10-13T07:38:19","guid":{"rendered":"https:\/\/blog.forumias.com\/?p=66390"},"modified":"2021-04-21T16:35:13","modified_gmt":"2021-04-21T11:05:13","slug":"pronuclear-transfer-can-be-used-for-prevention-of-mitochondrial-diseases-in-offspring","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/pronuclear-transfer-can-be-used-for-prevention-of-mitochondrial-diseases-in-offspring\/","title":{"rendered":"Pronuclear Transfer can be used for Prevention of mitochondrial diseases in offspring"},"content":{"rendered":"<p><b><span data-contrast=\"auto\">Pronucleus<\/span><\/b><b><span data-contrast=\"auto\">\u00a0is the nucleus of a sperm or an egg cell during the process of fertilization<\/span><\/b><span data-contrast=\"auto\">. The sperm cell becomes a pronucleus only after the sperm enters the ovum, but before the fusion of genetic material of the sperm and egg.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:1,&quot;335551620&quot;:1,&quot;335559739&quot;:160,&quot;335559740&quot;:360}\">\u00a0<\/span><\/p>\n<p>The technique of pronuclear transfer involves the transfer of\u00a0pronuclei from one zygote to another. Under this technique, first This technique first the healthy donated egg\/s (provided by the mitochondrial donor) is fertilised with the intending male parent sperm.<\/p>\n<p><b><span data-contrast=\"auto\">Pronuclear\u00a0<\/span><\/b><b><span data-contrast=\"auto\">Transfer<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">has the potential to prevent mitochondrial disease in the offspring as\u00a0<\/span><b><span data-contrast=\"auto\">Mitochondrial DNA is transmitted maternally<\/span><\/b><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">In pronuclear transfer, the\u00a0<\/span><span data-contrast=\"auto\">mother\u2019s\u00a0<\/span><span data-contrast=\"auto\">egg is first fertilized with the sperm which produces a zygote. The pronuclei of the egg and sperm are then removed from the zygote and inserted into a\u00a0<\/span><b><span data-contrast=\"auto\">donor egg that has been fertilized and has had its own nucleus removed<\/span><\/b><span data-contrast=\"auto\">. The zygote derived from the donor egg is then implanted into the mother\u2019s uterus.<\/span><br \/>\n<span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:1,&quot;335551620&quot;:1,&quot;335559739&quot;:160,&quot;335559740&quot;:360}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pronucleus\u00a0is the nucleus of a sperm or an egg cell during the process of fertilization. The sperm cell becomes a pronucleus only after the sperm enters the ovum, but before the fusion of genetic material of the sperm and egg.\u00a0 The technique of pronuclear transfer involves the transfer of\u00a0pronuclei from one zygote to another. Under&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/pronuclear-transfer-can-be-used-for-prevention-of-mitochondrial-diseases-in-offspring\/\">Continue reading <span class=\"screen-reader-text\">Pronuclear Transfer can be used for Prevention of mitochondrial diseases in offspring<\/span><\/a><\/p>\n","protected":false},"author":10308,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1227],"tags":[],"class_list":["post-66390","post","type-post","status-publish","format-standard","hentry","category-science-and-technology","entry"],"jetpack_featured_media_url":"","views":{"total":21,"cached_at":1698382897,"cached_date":1698470218},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/66390","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/10308"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=66390"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/66390\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=66390"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=66390"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=66390"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}