{"id":68611,"date":"2020-11-03T18:04:41","date_gmt":"2020-11-03T12:34:41","guid":{"rendered":"https:\/\/blog.forumias.com\/?p=68611"},"modified":"2021-03-05T12:54:42","modified_gmt":"2021-03-05T07:24:42","slug":"serological-surveys","status":"publish","type":"post","link":"https:\/\/forumias.com\/blog\/serological-surveys\/","title":{"rendered":"Serological surveys"},"content":{"rendered":"<p class=\"LC20lb DKV0Md\"><strong><span style=\"font-size: 14pt;\">What are serological surveys<\/span><\/strong><\/p>\n<p><strong>Context:<\/strong>\u00a0The Indian Council of Medical Research conducted two serosurveys: May 11 to June 4 and August 17 to September 22.<\/p>\n<p><strong>What is serological survey?<\/strong><\/p>\n<ul>\n<li>Serological surveys are used to detect the prevalence of antibodies against COVID-19\/any diseases.<\/li>\n<li>Their purpose is to measure the proportion of a population already infected as evidenced by prevalence of antibody against the disease.<\/li>\n<\/ul>\n<p><strong>How serological surveys are carried out?<\/strong><\/p>\n<ul>\n<li>Statisticians stratify the population and select a random sample from all strata so that the prevalence figure obtained is representative of the whole population.<\/li>\n<li>Random samples are tested from the entire population then, the data are extrapolated to the whole population.<\/li>\n<\/ul>\n<p><strong>Why antibody is tested?<\/strong><\/p>\n<ul>\n<li>Antibodies are the evidence of the host\u2019s response to virus infection.<\/li>\n<li>Their presence in the blood-serum confirms past infection.<\/li>\n<\/ul>\n<p><strong>Why the data derived from serosurveys must be interpreted with caution<\/strong>?<\/p>\n<ul>\n<li><strong>Issue with Asymptomatic cases<\/strong>: Asymptomatic cases constitute more than 80% of those infected with the virus. In people with asymptomatic infections, these antibody levels decline over time and become undetectable by 60 days after proven infection.<\/li>\n<li><strong>Swift disappearance of S2 antibodies<\/strong>: In a study on exposure-prone healthcare workers in Tennessee, nearly half the subjects with S2 antibodies became negative in two months.<\/li>\n<li><strong>Inaccuracy<\/strong>: The latent period between infection and the appearance of a detectable antibody is about four weeks. Those who got infected recently before the survey may not be covered.<\/li>\n<li>If taken at face value, serosurveys may not reflect the true level of antibodies prevalence.<\/li>\n<\/ul>\n<p><strong>What is the way forward?<\/strong><\/p>\n<ul>\n<li>The predicted herd immunity level needed to end the epidemic was 60%. In India, according to the serological surveys, half of the herd immunity level required to end the epidemic was already reached by mid-September.<\/li>\n<li>However, during the festival the Governments must enforce strict norms regarding crowding, especially inside buildings.<\/li>\n<li>This will ensure safety of the individuals, family members particularly senior citizens.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>What are serological surveys Context:\u00a0The Indian Council of Medical Research conducted two serosurveys: May 11 to June 4 and August 17 to September 22. What is serological survey? Serological surveys are used to detect the prevalence of antibodies against COVID-19\/any diseases. Their purpose is to measure the proportion of a population already infected as evidenced&hellip; <a class=\"more-link\" href=\"https:\/\/forumias.com\/blog\/serological-surveys\/\">Continue reading <span class=\"screen-reader-text\">Serological surveys<\/span><\/a><\/p>\n","protected":false},"author":61,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"categories":[1230],"tags":[1315,1289,1456],"class_list":["post-68611","post","type-post","status-publish","format-standard","hentry","category-9-pm-daily-articles","tag-st_1","tag-soc_0","tag-soc_01","entry"],"jetpack_featured_media_url":"","views":{"total":0,"cached_at":"","cached_date":1704807672},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/68611","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/comments?post=68611"}],"version-history":[{"count":0,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/posts\/68611\/revisions"}],"wp:attachment":[{"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/media?parent=68611"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/categories?post=68611"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forumias.com\/blog\/wp-json\/wp\/v2\/tags?post=68611"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}