Universal Recipient

• A person who can accept a blood transfusion from any blood type is called a universal recipient.
• The immune system of a person with AB blood will accept blood from all possible donors, whether they have O, A, B, or AB blood.
• Blood contains red cells with type A antigen on their surface has in its serum (fluid) antibodies against type B red cells. If in transfusion, type B blood is injected into persons with type A blood, the red cells in the injected blood will be destroyed by the antibodies in the recipient’s blood.
• In the same way, type A red cells will be destroyed by anti-A antibodies in type B blood. Type O blood can be injected into persons with type A, B, or O blood unless there is incompatibility with respect to some other blood group system also present. Persons with type AB blood can receive type A, B, or O blood.

Source: NCERT