Q. Consider the following statements:
1.Colorectal cancer (CRC) is one of the common types of cancer found in India.
2.Fusobacterium nucleatum is a bacterium commonly found in the human brain.
3.Fusobacterium nucleatum help cancer cells in CRC to escape the immune system and spread within the gut.
Which of the statements given above are correct?
Explanation –
Statements 1 and 3 are correct. In India, CRC is the seventh most common type of cancer in India, with cases increasing by 20% from 2004 to 2014. This indicates that CRC is a significant health concern in India. Fusobacterium nucleatum has been shown to play a role in colorectal cancer (CRC) by helping cancer cells escape the immune system and spread within the gut. Studies have indicated that Fusobacterium nucleatum can modulate the tumor microenvironment, diminish adaptive immunity against colorectal cancers.
Statement 2 is incorrect. Fusobacterium nucleatum is not commonly found in the human brain. It is a gram-negative anaerobic bacterium that is indigenous to the human oral cavity and can also be found in the gastrointestinal tract.
Source: The Hindu
