CRIB- A new Human Blood group

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News: A new blood group, previously unidentified anywhere in the world, has been discovered in a South Indian woman from Kolar district in Karnataka.

About CRIB- A new Human Blood group

Source – Health Magazine
  • The CRIB blood group is a newly identified blood type outside the existing major systems like ABO and Rh.
  • Full form: In recognition of its origin, the group has been officially named ‘CRIB’, with CR representing Cromer and IB standing for India, Bengaluru.
  • System: It belongs to the INRA (Indian Rare Antigen) blood group system, which was officially recognized by the International Society of Blood Transfusion (ISBT) in 2022.
  • It is an entirely new antigen not fitting into the 43 known blood group systems previously recognized by the ISBT.
  • Characteristics
    • It is characterized by the absence of a high-prevalence antigen found in most people.
    • This absence of a common antigen makes blood transfusions extremely complex as only other CRIB-negative blood can be used, which is extremely rare.
  • Importance
    • It plays a crucial role in cases of Hemolytic Disease of the Fetus and Newborn (HDFN), where antibodies from the mother attack the red blood cells of the fetus.
    • Identifying the CRIB group early in such cases could help prevent life-threatening complications during pregnancy.
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