Rift Valley Fever (RVF)

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News: Recently, WHO confirmed an outbreak of Rift Valley Fever (RVF) affecting Mauritania and Senegal, resulting in over 404 human cases and 42 deaths.

About Rift Valley Fever (RVF)

Rift Valley Fever (RVF)
Source – Jenner Institute
  • RVF is a viral zoonotic disease that affects both animals and humans.
  • Caused by : The disease is caused by a Phlebovirus belonging to the Phenuiviridae family.
  • It primarily infects animals such as sheep, goats, cattle, and camels.
  • Transmission
    • Humans become infected through bites of infected mosquitoes or contact with blood, organs, or raw milk from infected animals.
    • There is no evidence of human-to-human transmission.
  • Incubation period: It is usually begin 2–6 days after exposure.
  • Symptoms
    • About 90% develop a mild, flu-like illness with high fever, headache, weakness, backache, and muscle and joint pain, sometimes with nausea, vomiting, and light sensitivity.
    • Severe disease is uncommon but includes:
      • Ocular disease (0.5–2%) causing blurred vision, floaters, eye pain, and possible permanent loss;
      • Meningoencephalitis (<1%) with confusion, dizziness, seizures, or coma; and
      • A haemorrhagic form (<1%) with jaundice, bleeding, and liver failure, carrying ~50% fatality.
  • Diagnosis
    • Diagnosing RVF is challenging because it mimics malaria, typhoid, and other febrile illnesses.
    • Confirmation requires laboratory testing using molecular or serological methods under high biosafety precautions.
  • Treatment
    • No specific antiviral treatment or licensed human vaccine is available.
    • Animal vaccination is useful between outbreaks but not during them.
  • Global classification
    • It is recognized by the World Organization for Animal Health as a notifiable animal disease.
    • It listed by WHO as a priority pathogen with epidemic potential.
  • Indian perspective
    • India has not reported any Rift Valley Fever outbreak till date.
    • It is classified as an exotic zoonosis under Indias One Health surveillance framework.
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