CALM-Brain

News: CALM-Brain was launched on March 25, 2026 as India’s first digital repository on psychiatric disorders to advance research, diagnosis, and treatment.

About CALM-Brain

• CALM-Brain is a first-of-its-kind open-source digital repository on brain structure and function in psychiatric disorders.
• Developed by: It has been developed by the National Institute of Mental Health and Neuro Sciences (NIMHANS) and the National Centre for Biological Sciences (NCBS) – TIFR under the Rohini Nilekani Centre for Brain and Mind (CBM).
• Objective: The main objective is to identify biomarkers, understand disease progression, and study treatment responses for better clinical outcomes.
• Features
  • Comprehensive data coverage: The repository integrates clinical, neuro-imaging, behavioural, and genetic datasets.
    • It covers major disorders such as addiction, bipolar disorder, dementia, obsessive compulsive disorder, and schizophrenia.
  • Large dataset base: It includes data from over 2,000 individuals across 900 families.
    • This enables comparison between affected and unaffected individuals for better analysis.
  • Biorepository linkage: The repository is linked with a stem cell biobank.
    • This supports research on the biological basis and origins of psychiatric disorders.
  • Open-source platform: The database will be available as an open-source platform for clinicians and researchers.
    • It helps in studying disease onset, progression, and underlying biological changes.