Q. Consider the following statements regarding Gene Silencing:
1.It is a process that reduces or prevents the expression of a gene without altering the underlying DNA sequence.
2.DNA methylation and RNA interference (RNAi) are two mechanisms through which gene silencing can occur.
3.Gene silencing techniques are purely theoretical and have not yet found practical applications in treating human diseases like cancer.
Which of the statements given above are correct?

[A] 1 and 2 only

[B] 2 and 3 only

[C] 1 and 3 only

[D] 1, 2 and 3

Answer: A
Notes:

Explanation:

  • Statements 1 and 2 are correct: These represent the epigenetic and RNA-mediated control of genes.
  • Statement 3 is incorrect: Gene silencing (especially via RNAi) is actively used in cancer research, treatments for neuro-degenerative disorders, and specialized clinical diagnosis.
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