Q. Consider the following statements regarding genetic disorders:
1.Single Gene Disorders, such as Cystic Fibrosis, follow simple inheritance patterns and are caused by defects in a specific gene.
2.Chromosome Disorders result solely from changes in the structure of chromosomes, while the total number of chromosomes always remains constant.
3.Multifactorial disorders like Cancer arise from complex interactions between multiple genes and environmental factors like lifestyle or toxins.
Which of the statements given above are correct?

[A] 1 and 2 only

[B] 2 and 3 only

[C] 1 and 3 only

[D] 1, 2 and 3

Answer: C
Notes:

Explanation:

  • Statement 1 is correct: These are caused by a mutation in one particular gene.
  • Statement 2 is incorrect: Chromosome disorders can result from changes in the number (e.g., Down’s syndrome has an extra chromosome 21) or the structure of chromosomes.
  • Statement 3 is correct: These involve multiple genes and external factors like diet or smoke.
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