Q. Consider the following statements regarding Reverse Vaccinology:
1.Reverse vaccinology uses genomic and bioinformatic information of a pathogen to identify potential vaccine targets, rather than relying primarily on conventional laboratory-based identification of antigens.
2.The approach can facilitate identification of vaccine candidates that may be difficult to discover using traditional methods, including antigens that are poorly expressed or difficult to culture.
Which of the statements given above is/are correct?
Answer: C
Notes:
Explanation: Both 1 and 2
Statement 1 is correct: Reverse vaccinology uses genomic sequencing, bioinformatics and computational analysis to identify potential vaccine antigens directly from a pathogen’s genome.
Statement 2 is correct: It can identify novel antigens that may be difficult to detect through conventional methods, including proteins that are poorly expressed or difficult to obtain through laboratory culture.
Source: TH
