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News: Researchers at IIIT-Delhi have developed AgeXtend to identify molecules with age defying properties. The research has been published in the journal ‘Nature Aging’.
About AgeXtend
- It is a platform based on Artificial Intelligence to discover molecules that promote healthy ageing.
- It has been developed by researchers at Indraprastha Institute of Information Technology, Delhi (IIIT-Delhi).
- Its aim is to identify molecules with age defying properties (geroprotectors), promoting healthy aging and longevity.
About the study
- The researchers screened over 1.1 billion compounds over a period of two years.
- Experiments were conducted on yeasts, worms (C. Elegans) and human cell models.
- The AI module evaluates geroprotective potential of molecules, assesses their safety and biological effects, ensuring both accuracy and safety.
- It is the largest study on the subject so far and involved scanning compounds from commercial drugs, Chinese drugs, Ayurveda and FDI approved molecules.
- The study also explored natural metabolites from the human microbiome and their potential role in combating cellular senescence.
