FLiRT variant

Source– This post on FLiRT variant has been created based on the article “All about FLiRT, the new COVID-19 variants” published in “The Hindu” on 9th May 2024.

Why in the news?

The COVID-19 cycle has regained momentum with the emergence of new ‘FLiRT’ variants. KP.2 and KP1.1 are descendants of the Omicron JN.1 variant, which proliferated worldwide.

About FLiRT Variants:

i) About FLiRT Variants: The FLiRT variants are new strains of the SARS-CoV-2 virus that have emerged in the United States. They are distant relatives of the Omicron variant.

ii) Variants: Two main strains have been identified within the FLiRT group: KP.2 and KP.1.1.

iii) Caused by: These variants were first detected in wastewater samples across the country and are descendants of the JN.1 lineage.

2. Reasons for Concern:

i) Scientists are concerned that KP.2 and KP.1.1 may be more adept at evading the immune system due to mutations in their spike proteins.

ii)  Factors such as waning immunity and suboptimal uptake of the latest COVID-19 vaccines raise concerns about a potential surge in infections during the summer.

3. Symptoms and Vaccination:

i) Symptoms: Symptoms associated with FLiRT variants largely mirror those of other COVID-19 strains, including fever, cough, fatigue, and respiratory difficulties.

ii) While vaccines remain effective against FLiRT variants, maintaining up-to-date booster shots is crucial to bolster protection against them.

4. Situation in India: India’s SARS-CoV-2 Genomics Consortium (INSACOG) has identified 238 cases of KP.2 and 30 cases of KP1.1 as of May 6. India has witnessed a resurgence in cases since early April, with a significant rise in positivity rates.

UPSC Syllabus: Science and technology (Health)