GLP-1 Receptor Agonists

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News: WHO has endorsed a new class of drug, GLP-1 Receptor Agonists, for managing obesity. 

About GLP-1 Receptor Agonists 

GLP-1 Receptor Agonists
Source- The Indian Express
  • Role: They mimic a hormone that regulates appetite and blood sugar level, lipid metabolism, and other biological functions. 
  • Drugs in this class include semaglutide and tirzepatide, which have potential to be transformative. 
  • Utility:  
    • Helps in treatment of Type 2 diabetes and obesity. 
    • These drugs can complement current policies promoting healthy eating and physical exercise to curb the obesity pandemic. 
    • These drugs are significant as obesity affects nearly 1 in 8 people worldwide. 
  • Side Effects: There are severe side effects like stomach paralysis, inflamed pancreas and thyroid cancer. 
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