Nephrotic Syndrome

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Source- This post on Nephrotic Syndrome is based on the article “In search of skin lightening creams, kidneys take a hit” published in “The Hindu” on 26th March 2024.

Why in the News?

Researchers from Kerala have reported a series of cases from Malappuram district where the regular use of fairness creams has been linked to nephrotic syndrome.

About Nephrotic Syndrome

Diagrammatic Representation of Health Condition Nephrotic syndrome
Source: Focus Medica

1. About Nephrotic syndrome: It is a kidney disorder characterized by excessive protein loss in urine due to issues with the kidneys’ filtration system, specifically the glomeruli.

2. Function of glomeruli: In healthy kidneys, glomeruli filter waste and excess fluids while retaining essential cells and proteins.

3. What happens in nephrotic syndrome: In nephrotic syndrome, inflamed glomeruli allow too much protein leakage. This condition can result from various kidney diseases or systemic disorders like diabetes or lupus.

4. Symptoms: Symptoms include severe swelling, foamy urine, high blood fat levels, weight gain, fatigue, and loss of appetite.

Complications may include blood clots, increased infection risk, high blood pressure, and potential kidney issues, such as chronic kidney disease or kidney failure.

5. Treatment: Treatment involves managing the underlying cause and addressing related concerns, including blood pressure control, cholesterol reduction, swelling mitigation, and infection prevention through medication and dietary adjustments.

UPSC Syllabus: Science and Technology (Health) 

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