Novel Oral Polio Vaccine Type 2 (nOPV2)

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News: The World Health Organization has granted prequalification to an additional Novel Oral Polio Vaccine Type 2 (nOPV2).

About Novel Oral Polio Vaccine Type 2 (nOPV2)

nOPV2 polio vax
Source: TOI
  • It is an improved oral vaccine designed to prevent outbreaks caused by circulating vaccine-derived poliovirus type-2.
  • The vaccine is used for active immunization in all age groups, especially during outbreaks of poliovirus type-2.
  • Developed By:  Global Polio Eradication Initiative
  • Type: Live-attenuated oral vaccine targeting Polio type 2
  • Aim of nOPV2
    • To stop outbreaks of poliovirus type-2 in a safer and more effective way.
    • To reduce the risk of vaccine-derived virus mutations.
    • To strengthen global progress toward the eradication of polio.
  • Key Features
    • The vaccine is genetically more stable than the traditional monovalent oral polio vaccine type-2.
    • The improved stability reduces the chance that the vaccine virus will mutate and cause new outbreaks.
    • The vaccine provides strong intestinal immunity, which helps stop virus transmission quickly.
    • It can be supplied in multi-dose vials (20- and 50-dose formats) suitable for high-volume vaccination programs.
    • It has a shelf life of up to 24 months and can be kept at routine vaccine storage temperatures, facilitating use across a range of environments.
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