Q. Consider the following statements about Fragile X syndrome (FXS):
1. Fragile X syndrome (FXS) is a genetic disorder.
2. The syndrome is the leading inherited cause of autism.
Which of the statements given above is/are correct?
Red Book
Red Book

[A] 1 only

[B] 2 only

[C] Both 1 and 2

[D] Neither 1 nor 2

Answer: C
Notes:

Fragile X syndrome (FXS) is a genetic disorder. It is also known as Martin-Bell syndrome or Marker X syndrome. The syndrome is the leading inherited cause of autism in 4% of the population worldwide. The syndrome is caused by changes in a gene called FMR1, which makes an important protein (FMRP). This protein is required for brain development. Children with Fragile X syndrome make too little or none of it. The symptoms are learning difficulty, speech delay, aggressive behaviour, hyperactivity, attention deficit, problems in motor skills, etc.

Source: EPIC September 2021

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