Q. Gram-negative bacteria are often more resistant to antibiotics compared to Gram-positive bacteria. Which one of the following best explains the reasons behind this?

[A] Gram-negative bacteria lack a cell wall

[B] The outer membrane of Gram-negative bacteria acts as a barrier

[C] Gram-negative bacteria have a thicker peptidoglycan layer

[D] Gram-negative bacteria can rapidly reproduce

Answer: B
Notes:

Explanation – Gram-negative bacteria possess an outer membrane that contains lipopolysaccharides, which act as a physical barrier to many antibiotics. This outer membrane prevents the entry of antibiotics into the bacterial cell, making Gram-negative bacteria generally more resistant to antibiotics compared to Gram-positive bacteria.

Source: The Hindu

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