Q. Which of the following is/are genome sequencing method/s?
1.Clone-by-Clone method
2.Whole genome shotgun sequencing
3.Next-Generation Sequencing
How many of the statements given above are correct?
Answer: C
Notes:
Explanation: Methods deployed for Genome sequencing: Clone-by-Clone method- It is a traditional method that requires high density genome map and works well for larger genomes like eukaryotic genomes.
- Whole genome shotgun sequencing- It is the improved version of Clone-by-Clone method that doesn’t require a genome map. It is the faster sequencing method but not suitable for larger genomes as they have many repetitive DNA sequences.
- Next-Generation Sequencing- It is the most advanced, robust, accurate, faster, cheaper and high throughput genome sequencing technique.
It relies on the chemistry of bridge amplification and can sequence more than 5 separate human genomes simultaneously. It is the most trusted Genome Sequencing method so far.
Source: FORUMIAS
