Q. With reference to Antibodies in human body, consider the following statements:
1.Antibodies recognize and attack antigens in order to remove them from the body.
2.IgM is the only isotype that can pass through the placenta.
Which of the statements given above is/are correct?
Red Book
Red Book

[A] 1 only

[B] 2 only

[C] .Both 1 and 2

[D] Neither 1 nor 2

Answer: A
Notes:
  • Statement 1 is correct: Antibody, also called immunoglobulin, is a protective protein produced by the immune system in response to the presence of a foreign substance, called an antigen. A wide range of substances are regarded by the body as antigens, including disease-causing organisms and toxic materials.
  • Statement 2 is incorrect: IgG is the main antibody in blood and it has a powerful ability to bind to bacteria and toxins, and thus it takes on an important role in the biological defense system. IgG is the only isotype that can pass through the placenta, and IgG transferred from the mother’s body protects a newborn

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