Q. With reference to cell-free DNA (cfDNA) consider the following statements:
1.cfDNA refers to small fragments of DNA that are found in the bloodstream or other bodily fluids, such as urine or saliva.
2.cfDNA can also be found within the nucleus of cells.
3.cfDNA can help in the early detection, diagnosis and treatment of cancers..
Which of the statements given above are correct?
Red Book
Red Book

[A] 1 and 2 only

[B] 2 and 3 only

[C] 1 and 3 only

[D] 1, 2 and 3

Answer: C
Notes:

Explanation –

Statements 1 and 3 are correct. cfDNA refers to small fragments of DNA that are found in the bloodstream or other bodily fluids, such as urine or saliva. cfDNA can help in the early detection, diagnosis and treatment of cancers.

Statement 2 is incorrect. Cell-free DNA, as the name suggests, is not contained within cells; instead, it is freely circulating in bodily fluids like blood, urine, and saliva.

Source: ForumIAS

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