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- The Indian Council of Medical Research (ICMR)’s
National Institute of Immunohematology, Mumbai, has developed a cost-effective
Point-of-Care (POC) rapid diagnostic test for severe Haemophilia A and Von
Willebrand Disease (VWD). This is the first in the world POC test for specific
diagnosis of any common bleeding disorder.
- The POC test is cost and time efficient. Working
cost of these kits is less than ₹50 whereas existing conventional test for the
diseases that costs around ₹4,000 to ₹10,000,
- Von Willebrand disease (VWD) and haemophilia A
are both bleeding disorders that prevent the blood from clotting. Haemophilia
A, also called factor VIII (FVIII) deficiency or classic haemophilia, is a
genetic disorder caused by missing or defective factor VIII, a clotting protein
- Von Willebrand disease (VWD) is a genetic
disorder caused by missing or defective von Willebrand factor (VWF), a clotting
protein. VWF binds factor VIII, a key clotting protein, and platelets in blood
vessel walls, which help form a platelet plug during the clotting process.
- Haemophilia A or VWD can cause life-threatening spontaneous
or post-traumatic bleeding like brain haemorrhage and gastrointestinal bleed bleeding
into joints or superficial bleeding from the nose or gums.
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