Apnoea Test

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News: The Supreme Court of India observed that a plea raised concerns that the apnoea test may not conclusively determine brain death.

About Apnoea Test

Apnoea Test
Source – CPAP
  • The apnoea test is considered an essential clinical test for determining brain death by assessing loss of brainstem function.
  • Aim: The aim is to confirm the absence of brainstem function by observing breathing response when carbon dioxide level rises.
  • Indicators: Absence of breathing effort at a carbon dioxide level of about 60 mmHg or a 20 mmHg rise from baseline supports brain death, while any breathing effort rules it out.
  • Key aspects:
    • Essential yet difficult test: It is considered a necessary condition for brain death, but it is difficult, lengthy, and may cause complications.
    • Prerequisites before test: The test requires stable conditions such as normal body temperature, proper oxygen level, normal carbon dioxide level, stable blood pressure, and absence of drugs affecting respiration.
    • Procedure and threshold: The test is considered positive when no breathing effort is seen at a carbon dioxide level of about 60 mmHg or a 20 mmHg rise from baseline.
    • Monitoring and Stopping Conditions: The test must be stopped if blood pressure falls below 90 mmHg, oxygen levels drop significantly, or cardiac arrhythmia occurs.
    • Complications and Risks: The test may cause hypotension, hypoxia, acidosis, pneumothorax, and cardiac complications, which may force stopping the test and affect diagnosis.
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