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News: PI Industries Ltd’s Pioxaniliprole, India’s first indigenously discovered insecticide molecule, has received approval from the Central Insecticides Board and Registration Committee (CIBRC) for use on rice, chilli, tomato and chana (chickpea) crops.
About Pioxaniliprole
- Pioxaniliprole is India’s first indigenously discovered insecticide molecule.
- Developed by: It has been developed by PI Industries Ltd.
- It will be launched in the coming Rabi (winter-spring) crop season.
- Class: It belongs to the anthranilic diamide class of insecticides, which acts on calcium-releasing channels in insects.
- Chemical composition and mechanism of action
- It is a carboxamide compound containing chlorine, nitrogen, oxygen and sulphur atoms.
- Its 20% w/v concentration means that the formulation contains 20 grams of the active ingredient per 100 ml of the product.
- It is available as a suspension concentrate (SC), a liquid formulation in which finely divided solid particles of the active ingredient are dispersed in water.
- It is designed to control insect pests, particularly caterpillar-type pests (larvae of moths and butterflies), affecting agricultural crops.
- How it works:
- It acts by targeting ryanodine receptors (RyRs), specialized protein channels present in insect muscle cells that regulate the release of calcium ions from intracellular storage compartments into the cell cytoplasm.
- Calcium ions play a crucial role in normal muscle contraction and relaxation.
- It binds to and activates these receptors, triggering an uncontrolled release of calcium ions.
- This disrupts normal muscle functioning in insects, leading to feeding cessation, lethargy, muscle paralysis and eventually death.
- Target insect pests: The insecticide is effective against yellow stem borer, leaf folder, fall armyworm, tobacco cutworm, fruit borer and pod borer.



