Pseudomonas Aeruginosa

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News– Recently, scientists from the Helmholtz Centre for Infection Research, Germany, discovered that a gene in the bacterium Pseudomonas aeruginosa exhibits bistable expression.

Pseudomonas Aeruginosa
Source- The Hindu

About Pseudomonas Aeruginosa

  • It is a gram-negative, aerobic, non-spore forming, rod-shaped bacterium.
  • It is commonly found in the environment, particularly freshwater.
  • It is capable of causing a variety of infections in both immunocompetent and immunocompromised hosts
  • It is a frequent cause of hospital-acquired infections, including ventilator-associated pneumonia and catheter-related urinary tract infections.
  • It also causes several community-acquired infections such as folliculitis, osteomyelitis (from puncture wounds), pneumonia, and otitis externa.
  • It is also a major cause of keratitis (eye infection).
Bistable Expression in Bacteria

  • Two bacteria with the same genetic makeup can still behave differently, like siblings with different personalities. One may keep a gene strongly “on,” while another keeps it weak or “off.” These patterns are inherited by offspring, a phenomenon called bistability.
  • Bistability works as a survival strategy, helping bacteria adapt to changing environments.
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